Mouse Cytokine Profiles Associated with Brucella Abortus RB51 Vaccination or B. Abortus 2308 Infection

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 2001 Sep 13

PMID 11553603

Citations 13

Authors

P Pasquali

R Adone

L C Gasbarre

C Pistoia

F Ciuchini

Affiliations

Soon will be listed here.

Abstract

This study indicated that mice immunized with Brucella abortus RB51 bacteria and subsequently challenged with B. abortus 2308 were protected from reinfection. After vaccination, both Th1 and Th2 cytokine patterns were observed. Of those, the early production of gamma interferon seems to have the prominent role in inducing an immunologically based protection.

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