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Lymphocyte Development from Hematopoietic Stem Cells

Overview
Publisher Elsevier
Specialties Biology
Genetics
Date 2001 Sep 5
PMID 11532393
Citations 24
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Abstract

The recent application of new techniques, such as multi-color cell sorting and the production of transgenic and gene-knockout mice, has contributed to a better understanding of lymphocyte development from hematopoietic stem cells. Now that we can purify progenitors at different maturational stages during lymphocyte development, the challenge is to understand the processes that govern each developmental stage transition.

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