Addition of Lithiated 9-deazapurine Derivatives to a Carbohydrate Cyclic Imine: Convergent Synthesis of the Aza-C-nucleoside Immucillins

Overview

Journal J Org Chem

Publisher American Chemical Society

Specialty Chemistry

Date 2001 Aug 21

PMID 11511245

Citations 15

Authors

G B Evans

R H Furneaux

T L Hutchison

H S Kezar

P E Morris Jr

V L Schramm

P C Tyler

Affiliations

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Abstract

Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.

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