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Probiotics and Functional Foods in Gastrointestinal Disorders

Overview
Specialty Gastroenterology
Date 2001 Jul 27
PMID 11470004
Citations 2
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Abstract

Probiotics are live microbial food supplements that benefit the host animal by improving intestinal microbial balance. When they are fed in yogurts, they can fall into the category of functional foods. Functional foods include these probiotics, prebiotics, and, to a certain extent, dietary fiber. Prebiotics are nondigestible food ingredients or supplements that alter the intestinal flora and stimulate the growth of healthy bacteria. Dietary fibers are part of plant foods that are nonstarch polysaccharides and are poorly digested or not digested by human enzymes. The physiologic process in which probiotics and functional foods affect the intestinal flora is through the balance of the intestinal microecology. This review looks at the four major components of intestinal microecology and describes the probiotics in use today and their clinical relevance. Although probiotics hold great promise and appear to be useful in some settings, more clinical study is needed to firmly establish the relevance of probiotic therapy.

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References
1.
Macfarlane G, Cummings J . Probiotics and prebiotics: can regulating the activities of intestinal bacteria benefit health?. BMJ. 1999; 318(7189):999-1003. PMC: 1115424. DOI: 10.1136/bmj.318.7189.999. View

2.
Isolauri E, Sutas Y, Kankaanpaa P, Arvilommi H, Salminen S . Probiotics: effects on immunity. Am J Clin Nutr. 2001; 73(2 Suppl):444S-450S. DOI: 10.1093/ajcn/73.2.444s. View

3.
Gibson G, Roberfroid M . Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995; 125(6):1401-12. DOI: 10.1093/jn/125.6.1401. View

4.
Bernet M, Brassart D, Neeser J, Servin A . Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria. Gut. 1994; 35(4):483-9. PMC: 1374796. DOI: 10.1136/gut.35.4.483. View

5.
McDONOUGH F, Hitchins A, Wong N, Wells P, Bodwell C . Modification of sweet acidophilus milk to improve utilization by lactose-intolerant persons. Am J Clin Nutr. 1987; 45(3):570-4. DOI: 10.1093/ajcn/45.3.570. View