Intramolecular 1,3-dipolar Cycloadditions of Norbornadiene-tethered Nitrile Oxides

Overview

Journal J Org Chem

Publisher American Chemical Society

Specialty Chemistry

Date 2001 Jun 30

PMID 11429911

Citations 3

Authors

C Yip

S Handerson

G K Tranmer

W Tam

Affiliations

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Abstract

Efficient routes to the synthesis of norbornadiene-tethered nitrile oxides have been developed, and their intramolecular 1,3-dipolar cycloadditions were studied. The cycloadditions occurred in good yields for a variety of substrates and were found to be highly regio- and stereoselective, giving single regio- and stereoisomers in most cases.

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