TNF and Receptors in Organ-specific Autoimmune Disease: Multi-layered Functioning Mirrored in Animal Models

Overview

Journal J Clin Invest

Specialty General Medicine

Date 2001 Jun 20

PMID 11413157

Citations 16

Authors

G Kassiotis

G Kollias

Affiliations

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References

Pasparakis M, Alexopoulou L, Episkopou V, Kollias G . Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune.... J Exp Med. 1996; 184(4):1397-411. PMC: 2192824. DOI: 10.1084/jem.184.4.1397. View

Hill G, Teshima T, Rebel V, Krijanovski O, Cooke K, Brinson Y . The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity. J Immunol. 2000; 164(2):656-63. DOI: 10.4049/jimmunol.164.2.656. View

Kassiotis G, Kollias G . Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination. J Exp Med. 2001; 193(4):427-34. PMC: 2195909. DOI: 10.1084/jem.193.4.427. View

Feldmann M, Maini R . Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?. Annu Rev Immunol. 2001; 19:163-96. DOI: 10.1146/annurev.immunol.19.1.163. View

Campbell I, ODonnell K, Lawlor K, Wicks I . Severe inflammatory arthritis and lymphadenopathy in the absence of TNF. J Clin Invest. 2001; 107(12):1519-27. PMC: 200197. DOI: 10.1172/JCI12724. View

Mori L, Iselin S, De Libero G, LESSLAUER W . Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient mice. J Immunol. 1996; 157(7):3178-82. View

Kollias G, Douni E, Kassiotis G, Kontoyiannis D . On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Immunol Rev. 1999; 169:175-94. DOI: 10.1111/j.1600-065x.1999.tb01315.x. View

Grewal I, Grewal K, Wong F, Picarella D, Janeway Jr C, Flavell R . Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells. J Exp Med. 1996; 184(5):1963-74. PMC: 2192884. DOI: 10.1084/jem.184.5.1963. View

van Oosten B, Barkhof F, Truyen L, Boringa J, Bertelsmann F, von Blomberg B . Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. Neurology. 1996; 47(6):1531-4. DOI: 10.1212/wnl.47.6.1531. View

10.

Cope A . Regulation of autoimmunity by proinflammatory cytokines. Curr Opin Immunol. 1999; 10(6):669-76. DOI: 10.1016/s0952-7915(98)80087-3. View

11.

Eugster H, Frei K, Bachmann R, Bluethmann H, Lassmann H, Fontana A . Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1. Eur J Immunol. 1999; 29(2):626-32. DOI: 10.1002/(SICI)1521-4141(199902)29:02<626::AID-IMMU626>3.0.CO;2-A. View

12.

Lenardo M, Chan K, Hornung F, McFarland H, Siegel R, Wang J . Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol. 1999; 17:221-53. DOI: 10.1146/annurev.immunol.17.1.221. View

13.

. TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group. Neurology. 1999; 53(3):457-65. View