Withanolide-type Steroids from Solanum Cilistum

Overview

Journal Phytochemistry

Publisher Elsevier

Specialties Biochemistry
Biology
Chemistry

Date 2001 Apr 21

PMID 11314962

Citations 6

Authors

X H Zhu

M Takagi

T Ikeda

K Midzuki

T Nohara

Affiliations

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Abstract

Six withanolide-type steroids, named as cilistols a, b, d, q, g and f, respectively, were isolated from the leaves of Solanum cilistum. The major component among them, cilistol a, was characterized as (22R, 24S, 25R, 26R)-1-oxo-22, 26; 24, 25-diepoxy-17alpha, 26-dihydroxyergost-2,5-diene on the basis of spectroscopic properties and X-ray crystallographic analysis; the other isolated compounds had closely related structures. This is the first report of withanolide-type steroids in the Solanum genera.

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