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Apoptosis in Oncology

Overview
Journal Cell Res
Specialty Cell Biology
Date 2001 Apr 18
PMID 11305320
Citations 16
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Abstract

Apoptosis is a complex process involving a large array of genes and mutation of any of these genes may lead to malignancy formation. Re-acquirement of FasL by tumor cells may enable them to evade the surveillance of immune system and thus contributes to the growth of tumor. Apart from traditional therapies, inducing apoptosis of tumor cell by new methods employing death receptor ligands and making use of Fas counterattack is also being developed.

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