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Higher-order Structure of Chromatin and Chromosomes

Overview
Publisher Elsevier
Specialties Biology
Genetics
Date 2001 Mar 16
PMID 11250134
Citations 92
Authors
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Abstract

The linear array of nucleosomes that comprises the primary structure of chromatin is folded and condensed to varying degrees in nuclei and chromosomes forming 'higher order structures'. We discuss the recent findings from novel experimental approaches that have yielded significant new information on the different hierarchical levels of chromatin folding and their functional significance.

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