Permeability Properties of the Postcapillary High-endothelial Venules in Lymph Nodes of the Mouse

Overview

Journal Lab Invest

Specialty Pathology

Date 1975 Feb 1

PMID 1113511

Citations 7

Authors

B van Deurs

C Ropke

E Westergaard

Affiliations

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Abstract

The permeability of the postcapillary high-endothelial venules in mice was investigated by light and electron microscopy. Experiments with intravenously injected horseradish peroxidase demonstrated a pronounced intercellular passage of this tracer. Vesicular transport was not observed. Additional experiments with lanthanum and tannic acid showed that no continous tight junctions sealed the intercellular spaces. However, some focal membrane appositions were observed.

Citing Articles

Electron microscopic study of the paracortical postcapillary "high endothelial venules" in lymph nodes of the normal calf.

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Ultrastructure and permeability of lymph node microvasculature in the mouse.

van Deurs B, Ropke C, Westergaard E Cell Tissue Res. 1976; 168(4):507-25.

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The influence of the lymph node on the protein concentration of efferent lymph leaving the node.

Quin J, Shannon A J Physiol. 1977; 264(2):307-21.

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