Series Introduction: the Transcription Factor NF-kappaB and Human Disease

Overview

Journal J Clin Invest

Specialty General Medicine

Date 2001 Jan 3

PMID 11134170

Citations 302

Authors

A S Baldwin Jr

Affiliations

Soon will be listed here.

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References

Patel A, Hanson J, McLean T, Olgiate J, Hilton M, Miller W . Herpes simplex type 1 induction of persistent NF-kappa B nuclear translocation increases the efficiency of virus replication. Virology. 1998; 247(2):212-22. DOI: 10.1006/viro.1998.9243. View

Ghosh S, May M, Kopp E . NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol. 1998; 16:225-60. DOI: 10.1146/annurev.immunol.16.1.225. View

Miagkov A, Kovalenko D, Brown C, Didsbury J, Cogswell J, Stimpson S . NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint. Proc Natl Acad Sci U S A. 1998; 95(23):13859-64. PMC: 24931. DOI: 10.1073/pnas.95.23.13859. View

Yin M, Yamamoto Y, Gaynor R . The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature. 1998; 396(6706):77-80. DOI: 10.1038/23948. View

Dumont A, Hehner S, Hofmann T, Ueffing M, Droge W, Schmitz M . Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB. Oncogene. 1999; 18(3):747-57. DOI: 10.1038/sj.onc.1202325. View

Traber K, Okamoto H, Kurono C, Baba M, Saliou C, Soji T . Anti-rheumatic compound aurothioglucose inhibits tumor necrosis factor-alpha-induced HIV-1 replication in latently infected OM10.1 and Ach2 cells. Int Immunol. 1999; 11(2):143-50. DOI: 10.1093/intimm/11.2.143. View

Wang C, Cusack Jr J, Liu R, Baldwin Jr A . Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nat Med. 1999; 5(4):412-7. DOI: 10.1038/7410. View

Moerman A, Mao X, Lucas M, Barger S . Characterization of a neuronal kappaB-binding factor distinct from NF-kappaB. Brain Res Mol Brain Res. 1999; 67(2):303-15. DOI: 10.1016/s0169-328x(99)00091-1. View

DeLuca C, Petropoulos L, Zmeureanu D, Hiscott J . Nuclear IkappaBbeta maintains persistent NF-kappaB activation in HIV-1-infected myeloid cells. J Biol Chem. 1999; 274(19):13010-6. DOI: 10.1074/jbc.274.19.13010. View

10.

Schneider A, Martin-Villalba A, Weih F, Vogel J, Wirth T, Schwaninger M . NF-kappaB is activated and promotes cell death in focal cerebral ischemia. Nat Med. 1999; 5(5):554-9. DOI: 10.1038/8432. View

11.

Yamamoto Y, Yin M, Lin K, Gaynor R . Sulindac inhibits activation of the NF-kappaB pathway. J Biol Chem. 1999; 274(38):27307-14. DOI: 10.1074/jbc.274.38.27307. View

12.

Barkett M, Gilmore T . Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene. 1999; 18(49):6910-24. DOI: 10.1038/sj.onc.1203238. View

13.

Rayet B, Gelinas C . Aberrant rel/nfkb genes and activity in human cancer. Oncogene. 1999; 18(49):6938-47. DOI: 10.1038/sj.onc.1203221. View

14.

Sun S, Ballard D . Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases. Oncogene. 1999; 18(49):6948-58. DOI: 10.1038/sj.onc.1203220. View

15.

Cahir McFarland E, Izumi K, Mosialos G . Epstein-barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-kappaB. Oncogene. 1999; 18(49):6959-64. DOI: 10.1038/sj.onc.1203217. View

16.

De Bosscher K, Vanden Berghe W, Vermeulen L, Plaisance S, Boone E, Haegeman G . Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell. Proc Natl Acad Sci U S A. 2000; 97(8):3919-24. PMC: 18117. DOI: 10.1073/pnas.97.8.3919. View

17.

Cominacini L, Pasini A, Garbin U, Davoli A, Tosetti M, Campagnola M . Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species. J Biol Chem. 2000; 275(17):12633-8. DOI: 10.1074/jbc.275.17.12633. View

18.

Karin M, Ben-Neriah Y . Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol. 2000; 18:621-63. DOI: 10.1146/annurev.immunol.18.1.621. View

19.

Baldwin Jr A . Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase. Cancer Res. 2000; 60(13):3477-83. View

20.

Nagaya T, Fujieda M, Otsuka G, Yang J, Okamoto T, Seo H . A potential role of activated NF-kappa B in the pathogenesis of euthyroid sick syndrome. J Clin Invest. 2000; 106(3):393-402. PMC: 314321. DOI: 10.1172/JCI7771. View