Frontiers in Chemical Genetics

Overview

Journal Trends Biotechnol

Specialty Biochemistry

Date 2000 Nov 4

PMID 11058785

Citations 14

Authors

B R Stockwell

Affiliations

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Abstract

New methods enable the identification of compounds that both induce a specific cellular state and lead to identification of proteins that regulate that state. Together, developments in three critical areas: chemical diversity, phenotype-based screening and target identification, enable the systematic application of this chemical genetic approach to almost any biological problem or disease process.

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