Effects of Glucose Repression of the Transmission and Recombination of Mitochondrial Genes in Yeast (Saccharomyces Cerevisiae)

Overview

Journal Genetics

Publisher Oxford University Press

Specialty Genetics

Date 1975 Aug 11

PMID 1104405

Citations 16

Authors

C W Birky Jr

Affiliations

Soon will be listed here.

Abstract

Matings of a number of Saccharomyces cerevisiae stocks give different output ratios of mitochondrial genotypes depending on whether the cells are glucose-repressed or derepressed. The effects of glucose repression are independent of cellular mating type and mitochondrial genotype, and take place at least in part after zygotes are formed. An explanation is proposed in terms of changes in the relative numbers of mitochondrial DNA molecules contributed by the a and alpha parents, modified by selective replication or destruction of molecules inside the zygote.

Citing Articles

Evolution of structural diversity of trichothecenes, a family of toxins produced by plant pathogenic and entomopathogenic fungi.

Proctor R, McCormick S, Kim H, Cardoza R, Stanley A, Lindo L PLoS Pathog. 2018; 14(4):e1006946.

PMID: 29649280 PMC: 5897003. DOI: 10.1371/journal.ppat.1006946.

Respiration deficient mutants in the A+T-rich region on yeast mitochondrial DNA containing the var1 gene.

Zassenhaus H, Perlman P Curr Genet. 2013; 6(3):179-88.

PMID: 24186543 DOI: 10.1007/BF00390336.

Identification of loci and functional characterization of trichothecene biosynthesis genes in filamentous fungi of the genus Trichoderma.

Cardoza R, Malmierca M, Hermosa M, Alexander N, McCormick S, Proctor R Appl Environ Microbiol. 2011; 77(14):4867-77.

PMID: 21642405 PMC: 3147405. DOI: 10.1128/AEM.00595-11.

Transcription of the yeast mitochondrial genome requires cyclic AMP.

McEntee C, Cantwell R, Rahman M, Hudson A Mol Gen Genet. 1993; 241(1-2):213-24.

PMID: 8232206 DOI: 10.1007/BF00280219.

Construction of a yeast mutant lacking the mitochondrial nuclease.

Zassenhaus H, Hofmann T, Uthayashanker R, Vincent R, Zona M Nucleic Acids Res. 1988; 16(8):3283-96.

PMID: 2836791 PMC: 336494. DOI: 10.1093/nar/16.8.3283.

References

Wickerham L . A Critical Evaluation of the Nitrogen Assimilation Tests Commonly Used in the Classification of Yeasts. J Bacteriol. 1946; 52(3):293-301. PMC: 518184. View

Wolf K, Dujon B, SLONIMSKI P . Mitochondrial genetics. V. Multifactorial mitochondrial crosses involving a mutation conferring paromomycin-resistance in Saccharomyces cerevisiae. Mol Gen Genet. 1973; 125(1):53-90. DOI: 10.1007/BF00292983. View

Coen D, Deutsch J, Netter P, Petrochilo E, SLONIMSKI P . Mitochondrial genetics. I. Methodology and phenomenology. Symp Soc Exp Biol. 1970; 24:449-96. View

Leblon G . Mechanism of gene conversion in Ascobolus immersus. II. The relationships between the genetic alterations in b 1 or b 2 mutants and their conversion spectrum. Mol Gen Genet. 1972; 116(4):322-35. DOI: 10.1007/BF00270089. View

Goldthwaite C, Cryer D, MARMUR J . Effect of carbon source on the replication and transmission of yeast mitochondrial genomes. Mol Gen Genet. 1974; 133(2):87-104. DOI: 10.1007/BF00264830. View