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Isoflavonoids from Pueraria Mirifica and Their Estrogenic Activity

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Journal Planta Med
Specialty Biology
Date 2000 Sep 14
PMID 10985090
Citations 21
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Abstract

Nine isoflavonoids including a new pterocarpene, puemiricarpene, were isolated from the tuberous root of Pueraria mirifica (Leguminosae). The structure of puemiricarpene was determined by spectroscopic means. Estrogenic activity of the isolated isoflavonoids was tested using MCF-7 human breast cancer cells. Moderate activity was observed for kwakhurin, a prenylated isoflavonoid.

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