Single-strand Scissions of Chromosomal DNA During Commitment to Recombination at Meiosis

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1975 May 1

PMID 1098045

Citations 15

Authors

G K Jacobson

R Pinon

R E Esposito

M S Esposito

Affiliations

Soon will be listed here.

Abstract

Diploid cells of the yeast Saccharomyces cerevisiae induced to undergo meiosis accumulate single-strand scissions in both template and newly synthesized DNA during commitment to genetic recombination. No evidence for accumulation of double-strand breaks during meiosis was obtained. When commitment to recombination is at the full meiotic level there are approximately 70 to 200 single-strand scissions per meiotic cell in which approximately 150 recombination events have been reported to occur.

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