» Articles » PMID: 10939308

Assessing Medication Appropriateness in the Elderly: a Review of Available Measures

Overview
Journal Drugs Aging
Specialties Geriatrics
Pharmacology
Date 2000 Aug 12
PMID 10939308
Citations 35
Authors
Affiliations
Soon will be listed here.
Abstract

The disproportionate use of medications, combined with age-related pharmacokinetic and pharmacodynamic changes, places older adults at high risk for medication related problems (MRPs). MRPs demonstrate significant morbidity, mortality and economic impact among healthcare systems. The negative outcomes associated with MRPs emphasise the need for more careful and thorough assessments of drug therapy among older adults. In the 1990s a number of methods and instruments were developed to assist in the assessment of medication appropriateness. These tools may be categorised by criteria as: implicit, explicit or one utilising a combination of implicit and explicit criteria. This article reviews these available tools and outlines the advantages and disadvantages of each. In conclusion, those instruments considered to be comprised of both implicit and explicit criteria offer a more thorough assessment of medication appropriateness.

Citing Articles

Enhancing Medication Safety through Implementing the Qatar Tool for Reducing Inappropriate Medication (QTRIM) in Ambulatory Older Adults.

Alyazeedi A, Sherbash M, Algendy A, Stewart C, Soiza R, Alhail M Healthcare (Basel). 2024; 12(12).

PMID: 38921300 PMC: 11202920. DOI: 10.3390/healthcare12121186.


Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic.

Kosirova S, Urbankova J, Klimas J, Foltanova T BMC Geriatr. 2023; 23(1):567.

PMID: 37715169 PMC: 10504736. DOI: 10.1186/s12877-023-04260-y.


Determinants affecting medication adherence in the elderly: A qualitative study.

Bastani P, Bikineh P, Ravangard R, Rezaee R, Kavosi Z Aging Med (Milton). 2021; 4(1):35-41.

PMID: 33738378 PMC: 7954825. DOI: 10.1002/agm2.12132.


The analysis of the use of potentially inappropriate medications in elderly in the Slovak Republic.

Jankyova S, Rubintova D, Foltanova T Int J Clin Pharm. 2019; 42(1):100-109.

PMID: 31820202 DOI: 10.1007/s11096-019-00944-x.


Factors, influencing medication errors in prehospital care: A retrospective observational study.

Ramadanov N, Klein R, Schumann U, Aguilar A, Behringer W Medicine (Baltimore). 2019; 98(49):e18200.

PMID: 31804342 PMC: 6919435. DOI: 10.1097/MD.0000000000018200.


References
1.
Rochon P, Gurwitz J . Optimising drug treatment for elderly people: the prescribing cascade. BMJ. 1997; 315(7115):1096-9. PMC: 2127690. DOI: 10.1136/bmj.315.7115.1096. View

2.
Hsia Der E, Rubenstein L, Choy G . The benefits of in-home pharmacy evaluation for older persons. J Am Geriatr Soc. 1997; 45(2):211-4. DOI: 10.1111/j.1532-5415.1997.tb04510.x. View

3.
Cleeland C, GONIN R, Hatfield A, Edmonson J, Blum R, Stewart J . Pain and its treatment in outpatients with metastatic cancer. N Engl J Med. 1994; 330(9):592-6. DOI: 10.1056/NEJM199403033300902. View

4.
Chrischilles E, Foley D, Wallace R, Lemke J, Semla T, Hanlon J . Use of medications by persons 65 and over: data from the established populations for epidemiologic studies of the elderly. J Gerontol. 1992; 47(5):M137-44. DOI: 10.1093/geronj/47.5.m137. View

5.
Owens N, Fretwell M, Willey C, Murphy S . Distinguishing between the fit and frail elderly, and optimising pharmacotherapy. Drugs Aging. 1994; 4(1):47-55. DOI: 10.2165/00002512-199404010-00005. View