In-vitro Susceptibility of Aspergillus Spp. Isolates to Amphotericin B and Itraconazole

Overview

Journal J Antimicrob Chemother

Publisher Oxford University Press

Specialty Infectious Diseases

Date 1999 Dec 10

PMID 10588320

Citations 26

Authors

E Dannaoui

F Persat

M F Monier

E Borel

M A Piens

S Picot

Affiliations

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Abstract

The MICs of amphotericin B and itraconazole for 230 isolates of Aspergillus spp., comprising 156 Aspergillus fumigatus, 20 Aspergillus terreus, 22 Aspergillus flavus, 17 Aspergillus nidulans and 15 Aspergillus niger, were determined by a broth microdilution method with RPMI 1640 medium. No isolate was detected with an MIC of amphotericin B >2 mg/L. Itraconazole MICs >16 mg/L were detected for four Aspergillus fumigatus and one Aspergillus nidulans isolates.

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