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Single Nucleotide Polymorphism Libraries: Why and How Are We Building Them?

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Journal Mol Med Today
Date 1999 Nov 24
PMID 10562720
Citations 22
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Abstract

A great deal of time and money is currently being invested in the production of large libraries of single nucleotide polymorphisms (SNPs) - variations of one nucleotide between the DNA sequence of individuals. This review compares and contrasts the available sources of SNP data, and describes the rationale behind the SNP mapping efforts, from the study of common diseases to unraveling an individual's response to medication.

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