Update on Diagnosis, Management, and Prevention of Hepatitis B Virus Infection

Overview

Journal Clin Microbiol Rev

Publisher American Society for Microbiology

Specialty Microbiology

Date 1999 Apr 9

PMID 10194463

Citations 82

Authors

F J Mahoney

Affiliations

Soon will be listed here.

Abstract

Acute and chronic hepatitis B virus (HBV) infection is a leading cause of liver disease worldwide. It is estimated that approximately 350 million people worldwide have chronic HBV infection and that 1 million persons die each year from HBV-related chronic liver disease. In the past decade, significant progress in the understanding of the molecular virology and pathogenesis of HBV infection has been made. In addition, effective treatment modalities have been developed for persons with chronic infection. Worldwide, prevention of HBV transmission has become a high priority. In 1992, the Global Advisory Group to the World Health Organization recommended that all countries integrate hepatitis B vaccine into national immunization programs by 1997. Currently, 80 countries have done so and several others are planning to. Many countries have reported dramatic reductions in the prevalence of chronic HBV infection among children born since the hepatitis B vaccine was introduced into infant immunization schedules. Recent reports from Taiwan indicate a reduction in the incidence of liver cancer among children as a result of widespread hepatitis B vaccination programs.

Citing Articles

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Unravelling the mechanisms by which chronic hepatitis B infection is associated with an increased risk of gestational diabetes.

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Hepatitis B virus-induced hepatocellular carcinoma: a persistent global problem.

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Hepatitis B virus (HBV) serological patterns among the HBsAg negative hospital attendees screened for immunization.

Kafeero H, Ndagire D, Ocama P, Drago Kato C, Wampande E, Walusansa A Sci Rep. 2022; 12(1):7425.

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