Zuzanna Rzepka
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Explore the profile of Zuzanna Rzepka including associated specialties, affiliations and a list of published articles.
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51
Citations
393
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Recent Articles
1.
Rzepka Z, Janus M, Marciniec K, Rok J, Wrzesniok D
Int J Mol Sci
. 2025 Feb;
26(4).
PMID: 40004003
The ability to over-proliferate is a hallmark of cancer cells, so inhibiting proliferation is crucial for successful cancer treatment. Vitamin B12 (cobalamin) is among the factors necessary for replication of...
2.
Zawila T, Swolana D, Rok J, Rzepka Z, Wojtyczka R
Molecules
. 2025 Feb;
30(3).
PMID: 39942764
is a widely prevalent microorganism whose key virulence factors include a high ability to adhere to synthetic surfaces and the capacity to form biofilms. The widespread distribution of multidrug-resistant strains...
3.
Banach K, Kowalska J, Maszczyk M, Rzepka Z, Rok J, Wrzesniok D
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684359
Phototoxicity is a significant problem that occurs in a large part of the population and is often caused by commonly used pharmaceuticals, including over-the-counter drugs. Therefore, testing drugs with photosensitizing...
4.
Latka K, Kickinger S, Rzepka Z, Zareba P, Latacz G, Siwek A, et al.
ACS Chem Neurosci
. 2024 Oct;
15(21):4046-4054.
PMID: 39425769
Inhibitory neurotransmission mediated by γ-aminobutyric acid (GABA) plays an important role in maintaining body homeostasis. Disturbances in GABA signaling are implicated in a multitude of neurologic and psychiatric conditions, including...
5.
Rok J, Kowalska J, Rzepka Z, Banach K, Wrzesniok D
Chem Biol Interact
. 2024 Oct;
404:111268.
PMID: 39396721
Phototoxic reactions are among the most common skin-related adverse effects induced by drugs. It is believed that the binding of chemicals to melanin biopolymers is a significant factor influencing skin...
6.
Rzepka Z, Bober-Majnusz K, Hermanowicz J, Bebenek E, Chrobak E, Surazynski A, et al.
Molecules
. 2024 Sep;
29(18).
PMID: 39339403
There are scientific studies indicating that the attachment of an indole moiety to the triterpene scaffold can lead to increased anticancer potential. Lipophilicity is one of the factors that may...
7.
Rzepka Z, Rok J, Zdybel M, Pilawa B, Beberok A, Wrzesniok D
Toxicol In Vitro
. 2024 May;
98:105844.
PMID: 38740103
Streptomycin (STR) is an aminoglycoside antibiotic with a broad-spectrum of activity and ototoxic potential. The mechanism of STR-induced inner ear damage has not been fully elucidated. It was previously found...
8.
Bebenek E, Rzepka Z, Hermanowicz J, Chrobak E, Surazynski A, Beberok A, et al.
Int J Mol Sci
. 2024 Apr;
25(8).
PMID: 38674101
Betulonic acid (B(O)A) is a pentacyclic lupane-type triterpenoid that widely exists in plants. There are scientific reports indicating anticancer activity of B(O)A, as well as the amides and esters of...
9.
Karkoszka M, Rok J, Rzepka Z, Banach K, Kowalska J, Wrzesniok D
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38338717
Hypertension is known to be a multifactorial disease associated with abnormalities in neuroendocrine, metabolic, and hemodynamic systems. Poorly controlled hypertension causes more than one in eight premature deaths worldwide. Hydrochlorothiazide...
10.
Karkoszka M, Rok J, Kowalska J, Rzepka Z, Banach K, Wrzesniok D
Toxicol In Vitro
. 2023 Nov;
95:105745.
PMID: 38036073
The phototoxic effect of meloxicam (MLX) raises the question of the effect of the drug on the redox homeostasis of normal human skin cells. The main objective of the study...