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Zuoqin Yan

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Articles 52
Citations 641
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Recent Articles
1.
Huang J, Ma T, Wang C, Wang Z, Wang X, Hua B, et al.
Mol Med . 2024 Sep; 30(1):167. PMID: 39342093
Background: Glucocorticoid-associated osteonecrosis of the femoral head (GA-ONFH) is a progressive bone disorder which frequently results in femoral head collapse and hip joint dysfunction. Sclerostin (SOST) is principally secreted by...
2.
Zhang Y, Qi G, Yan Y, Wang C, Wang Z, Jiang C, et al.
J Gene Med . 2023 Mar; 25(8):e3510. PMID: 36998238
Background: Osteoarthritis (OA) is a prevalent degenerative articular disease for which there is no effective treatment. Progress has been made in mesenchymal stem cell (MSC)-based therapy in OA, and the...
3.
Jiang Z, Jin L, Jiang C, Yan Z, Cao Y
J Orthop Surg Res . 2023 Mar; 18(1):162. PMID: 36864451
Background: Despite extensive research, there is still a need for safe and effective agents to promote spinal fusion. Interleukin (IL)-1β is an important factor which influences the bone repair and...
4.
Li Y, Yang D, Gao X, Ju M, Fang H, Yan Z, et al.
Nutr Metab (Lond) . 2022 Dec; 19(1):84. PMID: 36578045
Background: Evidence from previous studies has suggested that ginger extract exhibits the potential as an alternative treatment for Coronavirus disease 2019 (COVID-19). Here, we want to investigate whether ginger supplement...
5.
Zhang Y, Wang X, Jiang C, Hua B, Yan Z
J Orthop Surg Res . 2022 Oct; 17(1):441. PMID: 36195938
Purpose: Hip preservation therapy of early ONFH (Osteonecrosis of the femoral head) has emerged as one of the hot areas of research. We have optimized the procedure of traditional MFCVBG...
6.
Wang C, Zhang Y, Wang Z, Yu W, Tong M, Yan Z
Tissue Cell . 2022 Sep; 79:101942. PMID: 36162153
Objective: The study aimed to establish whether HIF1α entrains the core clock in chondrocytes and how the HIF1α affects the circadian rhythm. Methods: We subjected primary chondrocytes to chronic circadian...
7.
Jiang Z, Wang H, Qi G, Jiang C, Chen K, Yan Z
IUBMB Life . 2022 May; 74(11):1052-1069. PMID: 35638167
Growing evidence indicates that iron overload is an independent risk factor for osteoporosis. However, the mechanisms are not fully understood. The purpose of our study was to determine whether iron...
8.
Xu L, Lin J, Liu Y, Hua B, Cheng Q, Lin C, et al.
Cell Rep . 2022 Apr; 39(2):110635. PMID: 35417690
Circadian genes such as Clock, Bmal1, Cryptochrome1/2, and Period1/2/3 constitute the precise circadian system. Clock is a commonly used mouse model harboring a circadian clock gene mutation, which lacks the...
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Jiang C, Wang X, Huang K, Chen L, Ji Z, Hua B, et al.
Rheumatology (Oxford) . 2021 May; 61(2):846-855. PMID: 33982084
Objective: To develop and validate a prediction model based on targeted sequencing for glucocorticoid (GC)-associated osteonecrosis of the femoral head (GA-ONFH) in GC-treated adults. Methods: This two-centre retrospective study was...