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Zhuwei Xu

Explore the profile of Zhuwei Xu including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 358
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Recent Articles
1.
Prajapati H, Xu Z, Eriksson P, Clark D
bioRxiv . 2025 Jan; PMID: 39803586
The eukaryotic genome is packaged into chromatin, which is composed of a nucleosomal filament that coils up to form more compact structures. Chromatin exists in two main forms: euchromatin, which...
2.
Prajapati H, Eriksson P, Elizalde P, Coey C, Xu Z, Clark D
Nat Struct Mol Biol . 2024 Nov; 32(2):247-256. PMID: 39587299
Eukaryotic genomes are packaged into chromatin, which is composed of condensed filaments of regularly spaced nucleosomes, resembling beads on a string. The nucleosome contains ~147 bp of DNA wrapped almost...
3.
Dennis A, Xu Z, Clark D
Nucleic Acids Res . 2024 Apr; 52(9):e45. PMID: 38634798
Recent studies have combined DNA methyltransferase footprinting of genomic DNA in nuclei with long-read sequencing, resulting in detailed chromatin maps for multi-kilobase stretches of genomic DNA from one cell. Theoretically,...
4.
Dennis A, Xu Z, Clark D
bioRxiv . 2023 Dec; PMID: 38076871
Recent studies have combined DNA methyltransferase footprinting of genomic DNA in nuclei with long-read sequencing, resulting in detailed chromatin maps for multi-kilobase stretches of genomic DNA from one cell. Theoretically,...
5.
Zhang W, Lazar-Stefanita L, Yamashita H, Shen M, Mitchell L, Kurasawa H, et al.
Mol Cell . 2023 Nov; 83(23):4424-4437.e5. PMID: 37944526
Whether synthetic genomes can power life has attracted broad interest in the synthetic biology field. Here, we report de novo synthesis of the largest eukaryotic chromosome thus far, synIV, a...
6.
Gale A, Pavesic M, Nickels T, Xu Z, Cormack B, Cunningham K
mSphere . 2023 Jun; 8(4):e0025423. PMID: 37358297
is a prominent opportunistic fungal pathogen of humans. The increasing incidence of infections is attributed to both innate and acquired resistance to antifungals. Previous studies suggest the transcription factor Pdr1...
7.
Gale A, Pavesic M, Nickels T, Xu Z, Cormack B, Cunningham K
bioRxiv . 2023 May; PMID: 37214952
Importance: is an opportunistic pathogenic yeast that causes discomfort and death. Its incidence has been increasing because of natural defenses to our common antifungal medications. This study explores the entire...
8.
Xu Z, Green B, Benoit N, Sobel J, Schatz M, Wheelan S, et al.
Mol Microbiol . 2021 Mar; 116(1):260-276. PMID: 33713372
Candida glabrata is an opportunistic pathogen of humans, responsible for up to 30% of disseminated candidiasis. Adherence of C. glabrata to host cells is mediated by adhesin-like proteins (ALPs), about...
9.
Xu Z, Green B, Benoit N, Schatz M, Wheelan S, Cormack B
Mol Microbiol . 2020 Feb; 113(6):1209-1224. PMID: 32068314
Candida glabratais an opportunistic pathogen in humans, responsible for approximately 20% of disseminated candidiasis. Candida glabrata's ability to adhere to host tissue is mediated by GPI-anchored cell wall proteins (GPI-CWPs);...
10.
Zhang R, Zeng H, Zhang Y, Chen K, Zhang C, Song C, et al.
Oncotarget . 2016 Mar; 7(15):19251-64. PMID: 26942885
Treatment targeting CD226 can ameliorate experimental autoimmune encephalomyelitis (EAE), the widely accepted model of MS. However, the mechanisms still need to be elucidated. Here we showed that CD226 blockage by...