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Zhongyuan Wen

Explore the profile of Zhongyuan Wen including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 174
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Recent Articles
1.
Tang J, Wen Z, Zhai M, Zhang J, Zhang S, Cui Y, et al.
Int J Biol Macromol . 2024 Apr; 269(Pt 1):131748. PMID: 38670194
Bio-based shape memory materials have attracted wide attention due to their biocompatibility, degradability and safety. However, designing and manufacturing wearable bio-based shape memory films with excellent flexibility and toughness is...
2.
Li J, Huang Y, Yang X, Cai Y, Wang Y, Dai W, et al.
Mol Metab . 2024 Mar; 83:101927. PMID: 38553003
Objective: Hepatic insulin resistance, which leads to increased hepatic gluconeogenesis, is a major contributor to fasting hyperglycemia in type 2 diabetes mellitus (T2DM). However, the mechanism of impaired insulin-dependent suppression...
3.
Wang Y, Yi B, Wang S, Chen X, Wen Z
PeerJ . 2023 Jun; 10:e14570. PMID: 37359706
Purpose: To analyze the clinical characteristics and immune function parameters and to explore the effect of hyperglycemia on the immune function in patients with Corona Virus Disease 2019 (COVID-19) with...
4.
Cai Y, Chen X, Yi B, Li J, Wen Z
Obes Rev . 2022 Jul; 23(10):e13490. PMID: 35796566
Obesity, a burgeoning worldwide health system challenge, is associated with several comorbidities, including non-alcoholic fatty liver disease (NAFLD), diabetes, atherosclerosis, and osteoarthritis, leading to serious problems to people's health. Adenosine...
5.
Yi B, Fen G, Cao D, Cai Y, Qian L, Li W, et al.
Int J Infect Dis . 2021 Feb; 105:113-119. PMID: 33578019
Objective: To investigate the epidemiological dynamics, transmission patterns, and the clinical outcomes of Coronavirus disease 2019 (COVID-19) in familial cluster patients in Wuhan, China. Methods: Between January 22, 2020, and...
6.
Cai Y, Shi S, Yang F, Yi B, Chen X, Li J, et al.
Diabetes Res Clin Pract . 2020 Sep; 169:108437. PMID: 32920103
Aim: No study elucidated the role of fasting blood glucose (FBG) level in the prognosis
of coronavirus disease 2019 (COVID-19). Methods: This cohort study was conducted in a single center...
7.
Wen Z, Li J, Fu Y, Zheng Y, Ma M, Wang C
Obesity (Silver Spring) . 2020 Aug; 28(10):1932-1940. PMID: 32844579
Objective: This study aimed to elucidate the mechanism by which hypertrophic adipocytes regulate insulin signaling in cardiac myocytes. Methods: Palmitate was used to induce hypertrophic 3T3-L1 adipocytes. Exosomes were purified...
8.
Zhang Y, Fu Y, Zheng Y, Wen Z, Wang C
Adipocyte . 2020 Jul; 9(1):346-358. PMID: 32614631
Obesity is associated with insulin resistance, diabetes, and obesity-related metabolic disorders. Brown adipocytes have emerged as potential targets for the treatment of obesity and obesity-related diseases. However, changes that occur...
9.
Wang W, Yao J, Guo X, Guo Y, Yan C, Liu K, et al.
Curr Med Res Opin . 2020 Apr; 36(7):1107-1115. PMID: 32338063
DBPR108, a novel dipeptidyl-peptidase-4 inhibitor, has shown great antihyperglycemic effect in animal models. This study was to evaluate the efficacy and safety of DBPR108 monotherapy in type 2 diabetes mellitus...
10.
Zhang D, Liu H, Zhang Y, Li J, Fu Y, Zheng Y, et al.
Cell Commun Signal . 2020 Apr; 18(1):60. PMID: 32272950
Adiponectin, an adipokine produced and secreted by adipocytes, is involved in regulating the development and progression of insulin resistance, diabetes, and diabetic complications. Heat shock protein 60 (HSP60) is a...