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Zhongying Zhang

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Articles 70
Citations 628
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Recent Articles
1.
Cheng Z, Huang K, Wang C, Chen L, Li X, Hu Z, et al.
Science . 2025 Mar; 387(6738):1083-1090. PMID: 40048532
Deconstructive transformation of carbon-carbon double bonds (C=C) is a pivotal strategy in synthetic chemistry and drug discovery. Despite the substantial advances in olefin metathesis and ozonolysis for natural product synthesis...
2.
Wang T, Ma L, Zhang L, Zhang Z, Zhai W, Li Y
Alpha Psychiatry . 2025 Jan; 25(6):721-726. PMID: 39830050
Objective: The objective is to investigate the situation and risk factors of depression in aged, hospitalized patients with chronic heart failure (CHF). Methods: A total of 196 aged CHF patients...
3.
Zhang L, Lin Y, Zhang Z, Chen Y, Zhong J
Front Immunol . 2024 Dec; 15:1444884. PMID: 39664383
Sepsis is a life-threatening syndrome characterized by organ dysfunction, resulting from an uncontrolled or abnormal immune response to infection, which leads to septicemia. It involves a disruption of immune homeostasis,...
4.
Lin Y, Zhao W, Pu R, Lv Z, Xie H, Li Y, et al.
Oncol Lett . 2024 Aug; 28(4):486. PMID: 39185489
Colorectal cancer (CRC) ranks as the 3rd most common cancer globally and is the 2nd leading cause of cancer-related death. Owing to the lack of specific early symptoms and the...
5.
Lin Y, Zhao W, Lv Z, Xie H, Li Y, Zhang Z
Front Oncol . 2024 Jul; 14:1419972. PMID: 39026978
CRC poses a significant challenge in the global health domain, with a high number of deaths attributed to this disease annually. If CRC is detected only in its advanced stages,...
6.
Zhang T, Wang T, Kou J, Zhang Z, Wang Y
J Multidiscip Healthc . 2024 Jun; 17:2847-2855. PMID: 38894964
Objective: This study evaluates a reengineered intervention aimed at improving the clinical management of intravenous indwelling needles in geriatric patients, focusing on cost-efficiency within the Diagnosis-Related Group (DRG) payment framework....
7.
Li H, Fang Y, Chen Y, Lin Y, Fang Z, Lin Z, et al.
Sci Rep . 2024 Jan; 14(1):2358. PMID: 38286794
CYP2C19 gene has multiple single nucleotide polymorphism (SNP), which is the major determinant for clopidogrel treatment responses. Therefore, CYP2C19 SNP detection is essential for predicting clopidogrel efficacy. Currently, there is...
8.
Yurube T, Buchser W, Zhang Z, Silwal P, Lotze M, Kang J, et al.
JOR Spine . 2024 Jan; 7(1):e1303. PMID: 38222800
Background: Low back pain is a global health problem that originated mainly from intervertebral disc degeneration (IDD). Autophagy, negatively regulated by the phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling...
9.
Lin Y, Xie H, Zhao W, Li Y, Zhang Z
Medicine (Baltimore) . 2023 Nov; 102(44):e35893. PMID: 37933010
Colorectal cancer (CRC) is a major cause of cancer-related deaths worldwide. NDUFAL42 is an important mitochondrial respiratory chain subunit that plays a critical role in cellular energy metabolism. However, the...
10.
Wang C, Fang X, Tang Z, Hua Y, Zhang Z, Gu X, et al.
Exp Gerontol . 2023 Aug; 180:112266. PMID: 37536575
Objective: To investigate the frailty, as estimated by accumulated health deficits, in association with the symptomatic carotid atherosclerosis and in relation to five-year cardiovascular (CVD) outcomes. Methods: This is a...