Zhongxing Huang
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Explore the profile of Zhongxing Huang including associated specialties, affiliations and a list of published articles.
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21
Citations
226
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Recent Articles
1.
Zhu X, Shi W, Huang Z, Shi L
Sensors (Basel)
. 2025 Jan;
25(2).
PMID: 39860910
This paper introduces a novel geometry-based synchrosqueezing S-transform (GSSST) for advanced gearbox fault diagnosis, designed to enhance diagnostic precision in both planetary and parallel gearboxes. Traditional time-frequency analysis (TFA) methods,...
2.
Zheng Y, Yang T, Chan K, Lin Z, Huang Z
Nat Chem
. 2024 Oct;
16(11):1845-1854.
PMID: 39367062
The high nitrogen content and diverse reactivity of malononitrile are widely harnessed to access nitrogen-rich fine chemicals. Although the facile substitutions of malononitrile can give structurally diverse quaternary carbons, their...
3.
Zheng W, Chen J, Qi X, Huang Z
Nat Chem
. 2023 Nov;
15(12):1672-1682.
PMID: 37973941
Stereoselective protonation is a challenge in asymmetric catalysis. The small size and high rate of transfer of protons mean that face-selective delivery to planar intermediates is hard to control, but...
4.
Shen L, Zheng Y, Lin Z, Qin T, Huang Z, Zi W
Angew Chem Int Ed Engl
. 2022 Dec;
62(8):e202217051.
PMID: 36562702
2-Aminoallyl cations are versatile 1,3-dipoles that could potentially be used for diverse (3+n) cycloaddition reactions. Despite some preliminary studies, the asymmetric catalytic transformation of these species is still underdeveloped. We...
5.
Liu H, Lau V, Xu P, Chan T, Huang Z
Nat Commun
. 2022 Aug;
13(1):4759.
PMID: 35963867
Amines and alcohols with a fully substituted α-carbon are structures of great value in organic synthesis and drug discovery. While conventional methods towards these motifs often rely on enantioselective carbon-carbon...
6.
Xu P, Shen C, Xu A, Low K, Huang Z
Angew Chem Int Ed Engl
. 2022 Jul;
61(37):e202208443.
PMID: 35880544
Diastereo- and enantioselective construction of vicinal stereocenters from easily available starting materials is a challenging task. Here, we report that a bifunctional catalyst prepared from dibutylmagnesium and a pipecolinol-derived tetradentate...
7.
Xu P, Liu S, Huang Z
J Am Chem Soc
. 2022 Apr;
144(15):6918-6927.
PMID: 35388689
Desymmetrization of easily available disubstituted malonic esters is a rewarding strategy to access structurally diverse quaternary stereocenters. Particularly, asymmetric reduction of malonic esters would generate a functional group with a...
8.
Zheng Y, Zhang S, Low K, Zi W, Huang Z
J Am Chem Soc
. 2022 Jan;
144(4):1951-1961.
PMID: 35076212
Enantioenriched tertiary alkyl halides are prevalent in bioactive molecules and can serve as versatile synthetic intermediates to construct complex structures. While conventional access to these motifs often hinges on stereoselective...
9.
Xu P, Huang Z
Nat Chem
. 2021 Jun;
13(7):634-642.
PMID: 34112991
Desymmetrization of fully substituted carbons with a pair of enantiotopic functional groups is a practical strategy for the synthesis of quaternary stereocentres, as it divides the tasks of enantioselection and...
10.
Trost B, Wang Y, Buckl A, Huang Z, Nguyen M, Kuzmina O
Science
. 2020 May;
368(6494):1007-1011.
PMID: 32467391
Bryostatins are a family of 21 complex marine natural products with a wide range of potent biological activities. Among all the 21 bryostatins, bryostatin 3 is structurally the most complex....