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Zhonglin Lu

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Articles 33
Citations 572
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Recent Articles
1.
Lu Z, Hu J, Chen G, Jiang H, Shih C, Afshar-Oromieh A, et al.
Med Phys . 2025 Feb; PMID: 39935268
Background: Bone marrow (BM) is the dominant dose-limiting organ in [Lu]Lu-PSMA-617 therapy for patients with metastasized castration resistant prostate cancer, where BM dosimetry is challenging due to segmentation. Purpose: We...
2.
Peng Z, Zhang F, Jiang H, Liu G, Sun J, Du Y, et al.
Quant Imaging Med Surg . 2024 Dec; 14(12):8140-8154. PMID: 39698633
Background: Deep-learning-based denoising improves image quality and quantification accuracy for low count (LC) positron emission tomography (PET). Conventional deep-learning-based denoising methods only require single LC PET image input. This study...
3.
Liu Y, Lu Z, Chen G, Shi K, Mok G
EJNMMI Phys . 2024 Nov; 11(1):93. PMID: 39528900
Background: The limited spatial resolution in SPECT images leads to partial volume effect (PVE), degrading the subsequent dosimetric accuracy. We aim to quantitatively evaluate PVE and partial volume corrections (PVC),...
4.
Ma X, Qian X, Ren R, Chen Y, Zhang H, Hao R, et al.
J Invest Surg . 2024 Oct; 37(1):2421826. PMID: 39467565
Background: Fracture healing can be impeded or even compromised by various factors, resulting in a growing number of patients suffering. The lncRNA LINC-PINT has garnered attention for its latent role...
5.
Jiang H, Du Y, Lu Z, Wang B, Zhao Y, Wang R, et al.
EJNMMI Phys . 2024 Jul; 11(1):60. PMID: 38985382
Purpose: I-Ioflupane SPECT is an effective tool for the diagnosis and progression assessment of Parkinson's disease (PD). Radiomics and deep learning (DL) can be used to track and analyze the...
6.
Lu Z, Polan D, Wei L, Aryal M, Fitzpatrick K, Wang C, et al.
J Nucl Med . 2024 Jul; 65(8):1224-1230. PMID: 38960710
Functional liver parenchyma can be damaged from treatment of liver malignancies with Y selective internal radiation therapy (SIRT). Evaluating functional parenchymal changes and developing an absorbed dose (AD)-toxicity model can...
7.
Chen G, Lu Z, Jiang H, Afshar-Oromieh A, Rominger A, Shi K, et al.
Front Med (Lausanne) . 2023 Nov; 10:1246881. PMID: 38020081
Background: Personalized dosimetry for Lu-177-PSMA treatment requires multiple-time-point SPECT/CT scans to calculate time-integrated activity (TIA). This study evaluates two-time-point (TTP) methods for TIA calculation for kidneys and tumors. Methods: A...
8.
Yang J, Deng J, Fan D, Chen G, Lu Z, Liu H, et al.
Clin Nucl Med . 2023 Jul; 48(10):847-852. PMID: 37418288
Purpose: We have developed a new pharmaceutical, ibandronic acid (IBA), and preliminarily demonstrated that it is an efficient bisphosphonate for the diagnosis and treatment of bone metastases. This study aims...
9.
Chen G, Lu Z, Jiang H, Lin K, Mok G
Sci Rep . 2023 Mar; 13(1):4020. PMID: 36899031
Partition model (PM) for Y-90 microsphere radioembolization is limited in providing 3D dosimetrics. Voxel-S-Values (VSV) method has good agreement with Monte Carlo (MC) simulations for 3D absorbed dose conversion. We...
10.
Lu Z, Chen G, Jiang H, Sun J, Lin K, Mok G
Eur J Nucl Med Mol Imaging . 2023 Mar; 50(8):2319-2330. PMID: 36877236
Purpose: Respiration and body movement induce misregistration between static [Tc]Tc-MAA SPECT and CT, causing lung shunting fraction (LSF) and tumor-to-normal liver ratio (TNR) errors for Y radioembolization planning. We aim...