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Zhongfa Liu

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Articles 58
Citations 2515
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Recent Articles
1.
Dwivedi P, Yuan S, Han S, Mangrio F, Zhu Z, Lei F, et al.
Artif Cells Nanomed Biotechnol . 2018 Oct; 46(sup3):S481-S491. PMID: 30299174
In our study, we have established a novel liquid-driven co-flow focusing (LDCF) process to fabricate curcumin (CUR)-loaded poly (lactic-co-glycolic acid) (PLGA) microparticles (CPMs). LDCF-CPMs of size 20.26 ± 2.37 μm...
2.
Sborov D, Canella A, Hade E, Mo X, Khountham S, Wang J, et al.
Leuk Lymphoma . 2017 Mar; 58(10):2310-2318. PMID: 28270022
Trial Registration: http://clinicaltrials.gov/ct2/show/NCT01129193.
3.
Cheng H, Xie Z, Jones W, Wei X, Liu Z, Wang D, et al.
AAPS J . 2016 Mar; 18(3):737-45. PMID: 26943915
AR-42, a new orally bioavailable, potent, hydroxamate-tethered phenylbutyrate class I/IIB histone deacetylase inhibitor currently is under evaluation in phase 1 and 2 clinical trials and has demonstrated activity in both...
4.
Yuan S, Lei F, Liu Z, Tong Q, Si T, Xu R
PLoS One . 2015 Jul; 10(7):e0132609. PMID: 26208167
Curcumin exhibits superior anti-inflammatory, antiseptic and analgesic activities without significant side effects. However, clinical dissemination of this natural medicine is limited by its low solubility and poor bio-availability. To overcome...
5.
Han B, Li S, Tong M, Holpuch A, Spinney R, Wang D, et al.
Cancer Prev Res (Phila) . 2015 Feb; 8(5):419-30. PMID: 25712051
The membrane-associated protein, focal adhesion kinase (FAK), modulates cell-extracellular matrix interactions and also conveys prosurvival and proliferative signals. Notably, increased intraepithelial FAK levels accompany transformation of premalignant oral intraepithelial neoplasia...
6.
Young N, Bruss M, Gardner M, Willis W, Mo X, Valiente G, et al.
PLoS One . 2014 Nov; 9(11):e111559. PMID: 25369140
Despite the widespread use of curcumin for centuries in Eastern medicine as an anti-inflammatory agent, its molecular actions and therapeutic viability have only recently been explored. While curcumin does have...
7.
Cao Y, Xu R, Liu Z
J Chromatogr B Analyt Technol Biomed Life Sci . 2014 Feb; 949-950:70-8. PMID: 24480327
Curcuminoids, a mixture of curcumin, demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC), have shown a variety of clinical benefits for several human chronic diseases including osteoarthritis, rheumatoarthritis, and type II diabetes. However,...
8.
Klisovic R, Blum W, Liu Z, Xie Z, Kefauver C, Huynh L, et al.
Leuk Lymphoma . 2013 Sep; 55(6):1332-6. PMID: 24015841
We hypothesized that GTI-2040, a 20-mer oligonucleotide complementary to the R2 subunit mRNA of ribonucleotide reductase, combined with high dose cytarabine (HiDAC) would result in enhanced cytotoxicity by favoring Ara-CTP...
9.
Christoforidis J, Xie Z, Jiang A, Wang J, Pratt C, Gemensky-Metzler A, et al.
Curr Eye Res . 2013 Apr; 38(7):761-6. PMID: 23548066
Purpose: To determine serum level differences of intravitreally-placed bevacizumab after vitrectomy and lensectomy-vitrectomy and to compare these with non-operated eyes in a rabbit model. Methods: Five Dutch-belted rabbits underwent pars...
10.
Liu Z, Ren C, Jones W, Chen P, Seminara S, Chan Y, et al.
J Chromatogr B Analyt Technol Biomed Life Sci . 2013 Mar; 926:1-8. PMID: 23524040
The kisspeptins are critical regulators of mammalian reproduction. Kisspeptin-10 ((45)YNWNSFGLRF-NH2(54), kisspeptin-112-121 or metastin 45-54, NSC 741805), an active fragment of kisspeptin, has been shown to be a potent stimulator of...