Zhongchan Sun
Overview
Explore the profile of Zhongchan Sun including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
375
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Recent Articles
1.
He W, He W, Zeng L, Zhao R, Qiu K, He P, et al.
Exp Cell Res
. 2025 Mar;
:114517.
PMID: 40089133
EtOH (Ethanol)-induced cardiotoxicity (EIC) is intimately associated with perturbed lipid metabolism. Lipid droplet-Mitochondria contacts (LD-Mito contacts) are important nodes in lipid metabolism. However, the roles of LD-Mito contacts in EIC...
2.
Wang R, Mo Y, Liang Y, Liu Y, Sun Z, Shang W, et al.
Drug Deliv Transl Res
. 2025 Mar;
PMID: 40053232
Coronary microcirculatory dysfunction, affecting over half of acute myocardial infarction (AMI) patients, correlates significantly with AMI prognosis. Nicorandil is an effective drug that markedly improves coronary microcirculation, but current clinical...
3.
He W, He W, Sun Z, He P
iScience
. 2025 Feb;
28(2):111539.
PMID: 39911348
PGAM5, a phosphatase found in mitochondria, is crucial for mitochondrial quality control (MQC) through its regulation on mitochondrial dynamics, biogenesis, and mitophagy. Previous studies have shown its involvement in multiple...
4.
He W, He W, Chen X, Zeng L, Zeng L, Liu Y, et al.
Biochem Pharmacol
. 2024 Aug;
229:116495.
PMID: 39159875
Doxorubicin (DOX)-induced cardiac damage remains a leading cause of death amongst cancer survivors. DOX-induced cardiotoxicity (DIC) is mediated by disturbed mitochondrial dynamics, but it remains debated that the mechanisms by...
5.
Sun Z, He W, Xia S, Tong G, Zeng L, Xue L, et al.
Rev Cardiovasc Med
. 2024 Jul;
23(12):408.
PMID: 39076662
Background: Peripheral arterial disease (PAD) can severely compromise limb vitality and function. Angiogenesis plays an important role in healing of ischemic lesions. Radiolabeled RGD (Arg-Gly-Asp) peptides specifically targeting integrin are...
6.
He W, Sun Z, Tong G, Zeng L, He W, Chen X, et al.
Theranostics
. 2024 Jul;
14(9):3719-3738.
PMID: 38948070
Autophagy dysregulation is known to be a mechanism of doxorubicin (DOX)-induced cardiotoxicity (DIC). Mitochondrial-Endoplasmic Reticulum Contacts (MERCs) are where autophagy initiates and autophagosomes form. However, the role of MERCs in...
7.
He W, Tong G, Fan H, Zhen C, Zeng L, Xue L, et al.
Exp Cell Res
. 2023 Jan;
423(2):113469.
PMID: 36627100
Ischemia-reperfusion (I/R) injury (IRI) is a common clinical consequence of myocardial infarction. Exendin-4 is a glucagon-like peptide-1 (GLP-1) analog that has been demonstrated to alleviate myocardial IRI. Autophagy, a lysosomal...
8.
Tong G, Zhao S, Wu J, Sun Z, Zhuang D, Chen Z, et al.
J Thorac Cardiovasc Surg
. 2022 Dec;
168(1):50-59.e6.
PMID: 36464509
Objective: The right axillary artery is currently recommended for arterial cannulation in surgery for acute type A aortic dissection. However, the feasibility of cannulation on a dissected right axillary artery...
9.
Tong G, Sun Z, Wu J, Zhao S, Chen Z, Zhuang D, et al.
Front Cardiovasc Med
. 2022 Apr;
9:835896.
PMID: 35360012
Background: The management of malperfusion is vital to improve the outcomes of surgery for acute type A acute aortic dissection (ATAAD). Open arch repair under hypothermic circulatory arrest with selective...
10.
Tong G, Wu J, Chen Z, Zhuang D, Zhao S, Liu Y, et al.
J Clin Med
. 2022 Mar;
11(6).
PMID: 35330018
Background: Coronary malperfusion (CM) secondary to acute type A aortic dissection (ATAAD) is considered rare but has a high mortality rate. This study examined the incidence, management, and outcomes of...