Zhizhong Guan
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Explore the profile of Zhizhong Guan including associated specialties, affiliations and a list of published articles.
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Citations
648
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Recent Articles
1.
Lan A, Gong Y, Li X, Wang Y, Zheng D, Tang H, et al.
Ecotoxicol Environ Saf
. 2024 Nov;
288:117366.
PMID: 39561566
In this study, we aimed to investigate the mechanism by which fluoride exposure causes bone damage and the relationship with the loss of dorsal longitudinal anastomotic vessel (DLAV) formation in...
2.
Song J, Zhao A, Li R, Luo Y, Dong Y, Wang C, et al.
BMC Genomics
. 2024 Sep;
25(1):908.
PMID: 39350036
Background: Coal-burning fluorosis is a chronic poisoning resulting from the prolonged use of locally available high-fluoride coal for heating and cooking. Prolonged fluoride exposure has been demonstrated to decrease PPARGC1A...
3.
Deng J, Zeng X, Zhang K, Zhang T, Dong Y, Zou J, et al.
Biol Trace Elem Res
. 2024 Aug;
PMID: 39106008
This study aimed to explore the role of histone methyltransferase SET and MYND domain containing 3 (SMYD3) in bone metabolism of osteoblasts exposed to fluoride. The levels of urine fluoride,...
4.
Zheng J, Li Y, Zhang T, Fu Y, Long P, Gao X, et al.
Neural Regen Res
. 2024 Jul;
20(5):1455-1466.
PMID: 39075912
JOURNAL/nrgr/04.03/01300535-202505000-00028/figure1/v/2024-07-28T173839Z/r/image-tiff Several studies have shown that activation of unfolded protein response and endoplasmic reticulum (ER) stress plays a crucial role in severe cerebral ischemia/reperfusion injury. Autophagy occurs within hours after...
5.
Tang Z, Chen Z, Guo M, Peng Y, Xiao Y, Guan Z, et al.
Mol Neurobiol
. 2024 Feb;
61(10):7517-7533.
PMID: 38401046
Oxidative stress is involved in the pathogenesis of Alzheimer's disease (AD), which is linked to reactive oxygen species (ROS), lipid peroxidation, and neurotoxicity. Emerging evidence suggests a role of nuclear...
6.
Luo S, Shao R, Hong Y, Zhang T, Zhou Q, Zhou Q, et al.
Front Microbiol
. 2024 Feb;
15:1296753.
PMID: 38380100
Dental fluorosis, resulting from long-term environmental exposure to fluoride, is prevalent among diverse populations worldwide. Severe fluorosis not only compromises the aesthetic appeal of teeth but also impairs their functionality....
7.
Ma Y, Liu Y, Liu X, Li M, Cui J, Guan Z, et al.
Int J Environ Health Res
. 2023 Nov;
34(8):2863-2876.
PMID: 37921081
To investigate the relationship between fluoride exposure and Osteochondroma (OC) prevalence, a cross-sectional study was conducted in drinking water endemic fluorosis areas of Heilongjiang Province, China. Our study first reported...
8.
Meng X, Wang J, Liu Y, Li M, Guan Z, Sowanoua A, et al.
Environ Geochem Health
. 2023 Sep;
45(11):8735-8747.
PMID: 37715839
Previous studies indicate that fluoride in drinking water has a toxic effect on cartilage and skeleton, which triggers osteoarthritis (OA) of which the most frequent is knee OA (KOA). A...
9.
Gao Y, Liu Y, Jiang Y, Qin M, Guan Z, Gao Y, et al.
Int J Environ Health Res
. 2023 May;
34(3):1410-1420.
PMID: 37211801
To evaluate the association between ATP2B1 gene polymorphisms and skeletal fluorosis, a cross-sectional study was conducted. In China, 962 individuals were recruited, including 342 cases of skeletal fluorosis. Four TP2BA1...
10.
Dong Y, Sun X, He W, Xiang J, Qi X, Hong W, et al.
Biol Trace Elem Res
. 2023 May;
202(2):538-547.
PMID: 37193858
To reveal the molecular mechanism of brain damage induced by chronic fluorosis, expression of PTEN-induced kinase 1 (PINK1)/parkin RBR E3 ubiquitin-protein ligase (Parkin)-mediated mitophagy pathway and activity of mitochondrial superoxide...