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Zhiyuan Wen

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Articles 58
Citations 2488
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Recent Articles
1.
Guan H, Tao H, Luo J, Wan L, Hu H, Chen L, et al.
Mol Cell Biochem . 2025 Feb; PMID: 39960585
The transcription factor YY1 is significantly upregulated in M2 macrophages, which can facilitate the malignant progression of multiple cancers. However, the precise mechanisms underlying the influence of YY1-high M2 macrophages...
2.
Wen Z, Liu Z, Bu H, Liu Y, Zhu J, Hu F, et al.
Fungal Biol . 2024 Oct; 128(7):2102-2112. PMID: 39384280
Cordyceps chanhua, an important cordycipitoid medical mushroom with wide use in Asia, has gained attention for its bioactive component beauvericin (BEA), which is of medicinal value as a drug lead,...
3.
Huo H, Wang J, Li C, Xiao S, Wang H, Ge J, et al.
Front Cell Infect Microbiol . 2024 Oct; 14:1468775. PMID: 39364147
Minks, cats, and some other species of carnivores are susceptible of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and have a high risk of transmitting SARS-CoV-2 to humans. The...
4.
Wen R, Peng Y, Liang Y, Wu Y, Li H, Chen Y, et al.
Ultrasound Med Biol . 2024 Aug; 50(11):1739-1744. PMID: 39181805
Objective: To assess the diagnostic efficacy of the CEUS LI-RADS combined with a model constructed on the basis of age, sex, AFP, and PIVKA-II (ASAP) for the diagnosis of HCC...
5.
Huang Z, Xie T, Xie W, Chen Z, Wen Z, Yang L
Front Oncol . 2024 Aug; 14:1428018. PMID: 39144829
Background: Lung cancer (LC) is one of the most common malignant tumors in the world and the leading cause of cancer-related deaths, which seriously threatens human life and health as...
6.
Khan I, Li S, Tao L, Wang C, Ye B, Li H, et al.
Nat Commun . 2024 Jan; 15(1):162. PMID: 38167417
SARS-CoV-2 and filovirus enter cells via the cell surface angiotensin-converting enzyme 2 (ACE2) or the late-endosome Niemann-Pick C1 (NPC1) as a receptor. Here, we screened 974 natural compounds and identified...
7.
Hou N, Shuai L, Zhang L, Xie X, Tang K, Zhu Y, et al.
ACS Cent Sci . 2023 Feb; 9(2):217-227. PMID: 36844503
The 3C-like protease (3CLpro) is an essential enzyme for the replication of SARS-CoV-2 and other coronaviruses and thus is a target for coronavirus drug discovery. Nearly all inhibitors of coronavirus...
8.
Wang X, Wen Z, Cao H, Luo J, Shuai L, Wang C, et al.
J Virol . 2023 Feb; 97(2):e0161122. PMID: 36779763
Identification of bona fide functional receptors and elucidation of the mechanism of receptor-mediated virus entry are important to reveal targets for developing therapeutics against rabies virus (RABV) and severe acute...
9.
Wang X, Wen Z, Cao H, Luo J, Shuai L, Wang C, et al.
J Virol . 2023 Feb; 97(2):e0161222. PMID: 36779762
Rabies virus (RABV) is a prototypical neurotropic virus that causes rabies in human and animals with an almost 100% mortality rate. Once RABV enters the central nervous system, no treatment...
10.
Wang W, Li W, Wen Z, Wang C, Liu W, Zhang Y, et al.
Adv Sci (Weinh) . 2022 Oct; 9(35):e2203499. PMID: 36266926
Outbreaks of coronaviruses (CoVs), especially severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have posed serious threats to humans and animals, which urgently calls for effective broad-spectrum antivirals. RNA-dependent RNA polymerase...