Zhiru Xu
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Explore the profile of Zhiru Xu including associated specialties, affiliations and a list of published articles.
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39
Citations
237
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Recent Articles
1.
Wang C, Wang Y, Dong Y, Duan Y, Zhang Y, Huang H, et al.
Bioconjug Chem
. 2025 Mar;
PMID: 40085485
Fibroblast growth factor 21 (FGF21) is a crucial regulator of glucose and lipid metabolism, showing significant therapeutic promise for metabolic disorders. However, its clinical application is limited by poor pharmacokinetics....
2.
Chang R, Xue F, Hou Z, Guo H, Cao L, Zhang S, et al.
Plant Physiol Biochem
. 2025 Mar;
222:109703.
PMID: 40054111
Nitrogen (N) availability is a key factor in plant growth, but the molecular mechanisms underlying the early responses of poplar (Populus × xiaohei T. S. Hwang & Liang) roots to...
3.
Zhang S, Cao L, Chen D, Chang R, Cao J, Zhang Q, et al.
Plant Biotechnol J
. 2025 Feb;
PMID: 39992899
Invertase (EC.3.2.1.26), a key enzyme in sucrose breakdown, is crucial for cellulose synthesis. However, the function of the vacuolar invertase (VINV) in woody plants remains unclear. In this study, transgenic...
4.
Wang Y, Shen L, Wang C, Dong Y, Hua H, Xu J, et al.
J Control Release
. 2024 Nov;
376:1130-1142.
PMID: 39510256
Optimizing the druggability of both native and AI-designed bioactive proteins is crucial for realizing their therapeutic potential. A key focus in designing protein-based therapeutics is improving their pharmacokinetic properties. However,...
5.
Leng X, Wang H, Cao L, Chang R, Zhang S, Xu C, et al.
J Exp Bot
. 2024 Mar;
75(13):4052-4073.
PMID: 38497908
The glutamine synthetase/glutamic acid synthetase (GS/GOGAT) cycle plays important roles in N metabolism, growth, development, and stress resistance in plants. Excess ammonium (NH4+) restricts growth, but GS can help to...
6.
Zhang S, Cao L, Chang R, Zhang H, Yu J, Li C, et al.
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38256092
Secondary development is a key biological characteristic of woody plants and the basis of wood formation. Exogenous nitrogen can affect the secondary growth of poplar, and some regulatory mechanisms have...
7.
Zhang S, Wang W, Chang R, Yu J, Yan J, Yu W, et al.
Int J Mol Sci
. 2023 Dec;
24(24).
PMID: 38139109
Exogenous nitrogen and carbon can affect plant cell walls, which are composed of structural carbon. Sucrose synthase (SUS), invertase (INV), hexokinase (HXK), phosphoglucomutase (PGM), and UDP-glucose pyrophosphorylase (UGP) are the...
8.
Yu J, Zhang X, Cao J, Bai H, Wang R, Wang C, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834448
The WRKY transcription factor (TF) family is one the largest plant-specific transcription factor families. It has been proven to play significant roles in multiple plant biological processes, especially stress response....
9.
Wang J, Song J, Qi H, Zhang H, Wang L, Zhang H, et al.
Plant Physiol Biochem
. 2023 Jul;
201:107876.
PMID: 37413942
Plant 2-cysteine peroxiredoxin (2-Cys Prx) is a mercaptan peroxidase localized in chloroplasts and has unique catalytic properties. To explore the salt stress tolerance mechanisms of 2-Cys Prx in plants, we...
10.
Cao M, Wang Z, Meng X, Xu Z, Gao J, Zhu W, et al.
J Int Med Res
. 2022 Dec;
50(12):3000605221139723.
PMID: 36514961
Objective: To evaluate the efficacy and safety of low-dose prourokinase (pro-UK) administration during primary percutaneous coronary intervention (PCI) for the treatment of acute ST-segment elevation myocardial infarction (STEMI) in patients...