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Zhenzhen Tu

Explore the profile of Zhenzhen Tu including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 28
Citations 154
Followers 0
Related Specialties
Biotechnology
Biomedical Engineering
Pathology
Top 10 Co-Authors
Haisheng Zhou
Yueqing Gu
Samuel Achilefu
Lifei Liu
Yanzhe Tan
Xingqin Tan
Siping Zhang
Wei Liu
Ying Xu
Shujuan Liu
Published In
J Vasc Access
J Nanosci Nanotechnol
J Cancer Res Clin Oncol
Med Sci Monit
Am J Perinatol
Affiliations
Soon will be listed here.
Recent Articles
1.
IL-6 Up-Regulates Expression of LIM-Domain Only Protein 4 in Psoriatic Keratinocytes through Activation of the MEK/ERK/NF-κB Pathway
Tu Z, Wei W, Zeng F, Wang W, Zhang Y, Zhang Y, et al.
Am J Pathol . 2024 Feb; 194(5):708-720. PMID: 38320628
Psoriasis is a chronic inflammatory skin disease characterized by the activation of keratinocytes and the infiltration of immune cells. Overexpression of the transcription factor LIM-domain only protein 4 (LMO4) promoted...
2.
Pro-inflammatory cytokine IL-6 regulates LMO4 expression in psoriatic keratinocytes via AKT/STAT3 pathway
Tu Z, Wei W, Xiang Q, Wang W, Zhang S, Zhou H
Immun Inflamm Dis . 2023 Dec; 11(12):e1104. PMID: 38156380
The transcription factor LIM-only protein 4 (LMO4) is overexpressed in the psoriatic epidermis and regulates keratinocyte proliferation and differentiation. High LMO4 expression levels are induced by interleukin-23 (IL-23) to activate...
3.
GPR108 is required for gambogic acid inhibiting NF-κB signaling in cancer
Lyu S, Zhang X, Tu Z, Zhou H, Ke X, Qu Y
Pharmacol Res . 2022 Jun; 182:106279. PMID: 35659621
GPCRs are the most potential targets for drug discovery, however, their role in oncology is underappreciated and GPCR-based anti-cancer drug is not fully investigated. Herein, we identified GPR108, a GPCR...
4.
A novel four-gene signature predicts immunotherapy response of patients with different cancers
Liu Y, Ni M, Li L, Wang J, Tu Z, Zhou H, et al.
J Clin Lab Anal . 2022 May; 36(7):e24494. PMID: 35588138
Background: Immune checkpoint blockade (ICB) therapy has demonstrated favorable clinical efficacy, particularly for advanced or difficult-to-treat cancer types. However, this therapy is ineffective for many patients displaying lack of immune...
5.
Photoswitchable probe with distinctive characteristics for selective fluorescence imaging and long-term tracing
Tu Z, Zhang Q, Xu X, Wang L, Qian Y, Huang W
RSC Adv . 2022 May; 9(9):4812-4815. PMID: 35514639
A photo-switchable and high-contrast bio-imaging indicator 4,4'-(1,1')-(4,4'-(cyclopentene-1,2-diyl)bis(5-methylthiophene-4,2-diyl))bis(methan-1-yl-1-ylidene)bis(azan-1-yl-1-ylidene)bis(2-(benzo[]thiazol-2-yl)phenol) (BMBT) has been demonstrated, by integrating photochromophore with excited-state intramolecular proton transfer (ESIPT) moiety. The ability of reversible emission switching enables arbitrarily selective...
6.
Both high glucose and phosphate overload promote senescence-associated calcification of vascular muscle cells
Zhang M, Li T, Tu Z, Zhang Y, Wang X, Zang D, et al.
Int Urol Nephrol . 2022 Apr; 54(10):2719-2731. PMID: 35396645
Purpose: The NAD-dependent deacetylase, sirtuin 1 (SIRT1), plays an important role in vascular calcification induced by high glucose and/or high phosphate levels. However, the mechanism by which SIRT1 regulates this...
7.
Ultrasound-Guided Cannulation of the Great Saphenous Vein in Neonates: A Randomized Study
Tu Z, Tan Y, Liu L, Xie J, Xu Y, Liu W
Am J Perinatol . 2021 Aug; 40(11):1217-1222. PMID: 34450674
Objective: This prospective randomized controlled study aimed to compare the ultrasound-guided (USG) technique with the standard single-wall puncture technique for epicutaneo-caval catheter (ECC) placement in neonates. Study Design: A total...
8.
Ultrasound guidance for internal jugular vein cannulation in neonates: Modified dynamic needle tip positioning short-axis out-of-plane technique versus long-axis in-plane technique, a randomized controlled trial
Tan Y, Tu Z, Ye P, Xu Y, Ye M, Bai L, et al.
J Vasc Access . 2021 May; 23(6):922-929. PMID: 33993790
Background: Ultrasound-guided central venous catheter placement has significantly improved the success rate of punctures and reduced the risk of complications. However, catheterizing the internal jugular vein under ultrasound guidance in...
9.
A negative feedback loop involving NF-κB/TIR8 regulates IL-1β-induced epithelial- myofibroblast transdifferentiation in human tubular cells
Jiang K, Zhang Y, He F, Zhang M, Li T, Tu Z, et al.
J Cell Commun Signal . 2021 May; 15(3):393-403. PMID: 33945104
Renal tubular epithelial-myofibroblast transdifferentiation (EMT) plays a central role in the development of renal interstitial fibrosis (RIF). The profibrotic cytokine interleukin (IL)-1 and the IL-1 receptor (IL-1R) also participate in...
10.
Distal superficial femoral vein versus axillary vein central catheter placement under ultrasound guidance for neonates with difficult access: A randomized clinical trial
Tan Y, Liu L, Tu Z, Xu Y, Xie J, Ye P
J Vasc Access . 2021 Apr; 22(4):642-649. PMID: 33908297
Background: Epicutaneo-caval catheters (ECCs) are extensively used in premature and ill neonates. This prospective, randomized, observational study aimed to compare the outcomes of ECC placement in the distal superficial femoral...