Zhengjiang Zhu
Overview
Explore the profile of Zhengjiang Zhu including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
486
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Recent Articles
1.
Gan X, Li X, Cai Y, Yin B, Pan Q, Teng T, et al.
Psychoneuroendocrinology
. 2024 Jun;
167:107086.
PMID: 38824765
Major depressive disorder (MDD) is a psychiatric illness that can jeopardize the normal growth and development of adolescents. Approximately 40% of adolescent patients with MDD exhibit resistance to conventional antidepressants,...
2.
Xu R, Ning Y, Ren F, Gu C, Zhu Z, Pan X, et al.
Nat Struct Mol Biol
. 2024 May;
31(10):1502-1508.
PMID: 38769387
Lysosomal transmembrane acetylation of heparan sulfates (HS) is catalyzed by HS acetyl-CoA:α-glucosaminide N-acetyltransferase (HGSNAT), whose dysfunction leads to lysosomal storage diseases. The mechanism by which HGSNAT, the sole non-hydrolase enzyme...
3.
Sun Y, Liu W, Su M, Zhang T, Li X, Liu W, et al.
Cell Death Discov
. 2024 Mar;
10(1):139.
PMID: 38485739
Esophageal squamous cell carcinoma (ESCC) remains an important health concern in developing countries. Patients with advanced ESCC have a poor prognosis and survival rate, and achieving early diagnosis remains a...
4.
Zhao H, Liu Y, Zhu Z, Feng Q, Ye Y, Zhang J, et al.
New Phytol
. 2023 Dec;
241(4):1574-1591.
PMID: 38062856
Fucoxanthin, a natural carotenoid that has substantial pharmaceutical value due to its anticancer, antioxidant, antiobesity, and antidiabetic properties, is biosynthesized from glyceraldehyde-3-phosphate (G3P) via a series of enzymatic reactions. However,...
5.
Chen S, Wu Y, Gao Y, Wu C, Wang Y, Hou C, et al.
Cell Rep
. 2023 Oct;
42(10):113246.
PMID: 37831605
Metastasis is the leading cause of high ovarian-cancer-related mortality worldwide. Three major processes constitute the whole metastatic cascade: invasion, intravasation, and extravasation. Tumor cells often reprogram their metabolism to gain...
6.
Zhang F, Zhang B, Ding H, Li X, Wang X, Zhang X, et al.
Adv Sci (Weinh)
. 2023 Jul;
10(27):e2207108.
PMID: 37469011
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with abnormal activation of the immune system. Recent attention is increasing about how aberrant lipid and cholesterol metabolism is linked together...
7.
Wang J, Zhou S, Cheng Y, Cheng L, Qin Y, Zhang Z, et al.
J Med Chem
. 2023 Feb;
66(4):2608-2621.
PMID: 36723914
There is growing interest in covalent targeted inhibitors in drug discovery against previously "undruggable" sites and targets. These molecules typically feature an electrophilic warhead that reacts with nucleophilic groups of...
8.
Li J, Cao Y, Niu K, Qiu J, Wang H, You Y, et al.
Mol Cell Proteomics
. 2022 Aug;
21(9):100276.
PMID: 35931320
Lysine acetylation is a reversible and dynamic post-translational modification that plays vital roles in regulating multiple cellular processes including aging. However, acetylome-wide analysis in the aging process remains poorly studied...
9.
You Y, Gao Y, Wang H, Li J, Zhang X, Zhu Z, et al.
Front Pharmacol
. 2021 Jan;
11:604404.
PMID: 33384603
Nicotinamide mononucleotide (NMN), a key precursory metabolite of NAD, has been shown to elevate the cellular level of NAD and ameliorate various age-related diseases. Despite these progresses, systemic evaluation pertaining...
10.
Guo L, Gao J, Gao Y, Zhu Z, Zhang Y
J Proteome Res
. 2020 Jan;
19(2):962-972.
PMID: 31922419
Aspirin, or acetylsalicylic acid (ASA), is the most widely used medication to relieve pain, fever, and inflammation. Recent studies have revealed new benefits of aspirin, including reduction of heart attack...