Zhengdong Cai
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Explore the profile of Zhengdong Cai including associated specialties, affiliations and a list of published articles.
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Articles
113
Citations
2098
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Recent Articles
1.
Mu H, Zhang Q, Zuo D, Wang J, Tao Y, Li Z, et al.
Cell Rep Med
. 2025 Feb;
:101977.
PMID: 39983717
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we identify a subgroup of OS with...
2.
Zhu Y, Yu X, Hao M, Wang Y, Fan G, Qian H, et al.
ACS Appl Bio Mater
. 2025 Feb;
PMID: 39943871
The repair and reconstruction of bone defects remain a challenge in orthopedics. Inadequate mechanical qualities, poor biocompatibility, and insufficient osteoconductivity are some of the issues facing current bone healing materials....
3.
Wang H, Jiang H, Tao Y, Yang B, Shen J, Mu H, et al.
Front Bioeng Biotechnol
. 2024 Nov;
12:1409988.
PMID: 39605750
Introduction: Osteosarcoma, characterized by high mortality and disability rates, poses a significant challenge due to its complex genetic background and the absence of specific membrane receptors, which hinder effective targeted...
4.
Yin H, Hu J, Gao J, Su T, Jin J, Jiang C, et al.
Cell Rep Med
. 2024 Oct;
5(10):101757.
PMID: 39368483
Chordoma is a rare and heterogeneous mesenchymal malignancy, with distinct clinical and biological behaviors. Till now, its comprehensive clinical-molecular characteristics and accurate molecular classification remain obscure. In this research, we...
5.
Xu W, Wang Z, Liu T, Ma X, Jiao M, Zhao W, et al.
J Ethnopharmacol
. 2024 Aug;
335:118709.
PMID: 39163893
Ethnopharmacological Relevance: Osteosarcoma (OS) is characterized by rapid growth and frequent pulmonary metastasis. Eurycoma longifolia Jack, a flowering plant primarily found in Southeast Asian countries, is commonly used in traditional...
6.
Gao Y, Wang Z, Jin X, Wang X, Tao Y, Huang S, et al.
Adv Healthc Mater
. 2024 May;
13(23):e2400538.
PMID: 38759954
Osteosarcoma (OS) is a "cold" tumor enriched in noninflammatory M2 phenotype tumor-associated macrophages (TAMs), which limits the efficacy of immunotherapy. The acidic tumor microenvironment (TME), generated by factors such as...
7.
Zhou H, Lou Y, Chen L, Kang Y, Liu L, Cai Z, et al.
Neural Regen Res
. 2023 Oct;
19(5):1126-1133.
PMID: 37862218
Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death. China has the largest population of patients with traumatic spinal cord injury. Previous studies...
8.
Zhou L, Zuo D, Wen J, Sun W, Cai Z, Zhang W, et al.
J Shoulder Elbow Surg
. 2023 Oct;
33(5):1040-1049.
PMID: 37844829
Background: Giant cell tumors of bone (GCTBs) are rare, aggressive tumors, and the proximal humerus is a relatively rare location for GCTBs; limited evidence exists on which surgical approaches and...
9.
Zan P, Shen J, Liu K, Wang H, Cai Z, Ma X, et al.
Front Pediatr
. 2023 Jul;
11:1168637.
PMID: 37416814
Purpose: To explore the application of Custom-made Semi-joint prosthesis replacement combined with Ligament Advanced Reinforcement System (LARS) ligament reconstruction for the limb salvage surgery (LSS) of malignant tumors in the...
10.
Ma X, Xu W, Jin X, Mu H, Wang Z, Hua Y, et al.
Eur J Pharmacol
. 2023 Jan;
942:175529.
PMID: 36690054
Osteosarcoma is the most common primary bone malignancy in children and adolescents; it exhibits rapid growth and a high metastatic potential and may thus lead to relatively high mortality. The...