Zheng-Yan Zhang
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Explore the profile of Zheng-Yan Zhang including associated specialties, affiliations and a list of published articles.
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19
Citations
209
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Recent Articles
1.
Han B, Li Z, Zhao X, Liang K, Mao Y, Zhang S, et al.
Nat Commun
. 2024 Oct;
15(1):9100.
PMID: 39438446
Obesity and related diseases pose a major health risk, yet current anti-obesity drugs inadequately addressing clinical needs. Here we show AA005, an annonaceous acetogenin mimic, resists obesity induced by high-fat...
2.
Zhang S, Wang X, Cai Q, Chen C, Zhang Z, Xu Y, et al.
Nat Metab
. 2024 Sep;
6(10):1991-2009.
PMID: 39322747
The crucial role of gut microbiota in shaping immunotherapy outcomes has prompted investigations into potential modulators. Here we show that oral administration of acarbose significantly increases the anti-tumour response to...
3.
Zhang S, Cheng L, Zhang Z, Sun H, Li J
Pharmacol Res
. 2022 Dec;
188:106633.
PMID: 36574857
The changes in gut microbiota have been implicated in colorectal cancer (CRC). The interplays between the host and gut microbiota remain largely unclear, and few studies have investigated these interplays...
4.
Zhang S, Han B, Mao Y, Zhang Z, Li Z, Kong C, et al.
Gut Microbes
. 2022 Mar;
14(1):2046246.
PMID: 35259052
The gut microbiota was emerging as critical regulatory elements in shaping the outcome of cancer immunotherapy. However, the underlying mechanisms by which the gut commensal species enhance antitumor immunity remain...
5.
Zhu X, Han G, Chen Q, Zhang Z, Wang L, Zhang B
Clin Exp Hypertens
. 2022 Feb;
44(4):306-312.
PMID: 35129024
Objective: The patient of hypertension and its complication increase fast in the past years. Obesity is thought to be a risk factor for hypertension, and BMI (body mass index) is...
6.
Chen H, Zeng Y, Zhang Z, Kong C, Zhang S, Li Z, et al.
J Inflamm Res
. 2021 Dec;
14:6175-6190.
PMID: 34853526
Background: Psoriasis is a chronic autoinflammatory skin disease, and its aetiology remains incompletely understood. Recently, gut microbial dysbiosis is found to be tightly associated with psoriasis. Objective: We sought to...
7.
Zhang Z, Zhang S, Chen H, Mao Y, Kong C, Li Z, et al.
Pathol Res Pract
. 2021 Nov;
228:153666.
PMID: 34749216
Clear cell renal cell carcinoma (ccRCC) is resistant to conventional therapy due to the deletion of the von Hippel-Lindau (VHL) gene, and novel treatment options are urgently needed. Here, using...
8.
Huang J, Mao Y, Han B, Zhang Z, Chen H, Li Z, et al.
Pharmacol Res
. 2021 Jun;
170:105726.
PMID: 34126228
Calorie restriction can modulate the gut microbiota and protect against many diseases including ischemic stroke. However, the role of calorie-restriction-induced microbiota alteration remained unknown in ischemic stroke rehabilitation. Here we...
9.
Zhang S, Mao Y, Zhang Z, Li Z, Kong C, Chen H, et al.
Theranostics
. 2021 Mar;
11(9):4155-4170.
PMID: 33754054
Anti-PD-1-based immunotherapy has emerged as a promising therapy for several cancers. However, it only benefits a small subset of colorectal cancer (CRC) patients. Mounting data supports the pivotal role of...
10.
Ma Y, Ling T, Su X, Jiang B, Nian B, Chen L, et al.
Food Chem
. 2020 Jul;
334:127560.
PMID: 32711271
Post-fermented Pu-erh tea (PFPT) is a microbially-fermented tea with distinct sensory qualities and multiple health benefits. Aspergillus are the dominant fungi in the fermentation and the main contributors to the...