Zhen-Yu She
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Explore the profile of Zhen-Yu She including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
393
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Recent Articles
1.
Xu Y, Chen J, Wang X, Huang M, Wei X, Luo X, et al.
Adv Biol (Weinh)
. 2025 Feb;
:e2400748.
PMID: 39957575
Microcephaly with or without chorioretinopathy, lymphedema, or impaired intellectual development (MCLMR; OMIM 152950) is a rare autosomal dominant disorder, which is primarily characterized by defects in the central nervous system...
2.
Chen J, He J, Wu S, Deng Z, Liu Y, Chen J, et al.
Andrology
. 2024 Dec;
PMID: 39737806
Background: The establishment of kinetochore-microtubule attachment is essential for error-free chromosome alignment and segregation during cell division. Defects in chromosome alignment result in chromosome instability, birth defects, and infertility. Kinesin-7...
3.
Chen J, Wu S, He J, Liu Y, Deng Z, Fang H, et al.
Cell Prolif
. 2024 Sep;
58(1):e13745.
PMID: 39266203
Chromosome congression and alignment are essential for cell cycle progression and genomic stability. Kinesin-7 CENP-E, a plus-end-directed kinesin motor, is required for chromosome biorientation, congression and alignment in cell division....
4.
Yang Y, Wei Y, She Z
Front Mol Biosci
. 2024 Apr;
11:1366113.
PMID: 38560520
Kinesin motors are a large family of molecular motors that walk along microtubules to fulfill many roles in intracellular transport, microtubule organization, and chromosome alignment. Kinesin-7 CENP-E (Centromere protein E)...
5.
Zhang J, Xu M, Chen J, Wei Y, She Z
Chromosoma
. 2024 Mar;
133(2):149-168.
PMID: 38456964
In eukaryotes, meiosis is the genetic basis for sexual reproduction, which is important for chromosome stability and species evolution. The defects in meiosis usually lead to chromosome aneuploidy, reduced gamete...
6.
Zhou Y, Xu M, Chen J, Zhang J, Wang X, Huang M, et al.
Exp Cell Res
. 2024 Feb;
436(1):113975.
PMID: 38367657
Kinesin motors play a fundamental role in development by controlling intracellular transport, spindle assembly, and microtubule organization. In humans, patients carrying mutations in KIF11 suffer from an autosomal dominant inheritable...
7.
Wei Y, Fan X, Lin X, Lin A, She Z, Wang X
Biochim Biophys Acta Mol Cell Res
. 2023 Jul;
1870(7):119555.
PMID: 37524262
KIFC1, a member of kinesin-14 subfamily motors, is essential for meiotic cell division and acrosome formation during spermatogenesis. However, the functions of KIFC1 in the formation and maintenance of the...
8.
Xu M, Chen J, Xu Y, Zhang J, Zhou Y, He J, et al.
J Vis Exp
. 2023 Jul;
(196).
PMID: 37427945
The CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 system has emerged as a powerful tool for precise and efficient gene editing in a variety of organisms. Centromere-associated protein-E (CENP-E) is...
9.
Yu W, Li Y, Xu M, Xu C, Chen J, Wei Y, et al.
Cell Death Discov
. 2022 Dec;
8(1):490.
PMID: 36513626
Chromosome stability relies on bipolar spindle assembly and faithful chromosome segregation during cell division. Kinesin-5 Eg5 is a plus-end-directed kinesin motor protein, which is essential for spindle pole separation and...
10.
She Z, Xu M, Jiang S, Wei Y
Biochim Biophys Acta Mol Cell Res
. 2022 Jun;
1869(9):119306.
PMID: 35680098
Genome stability depends on chromosome congression and alignment during cell division. Kinesin-7 CENP-E is critical for kinetochore-microtubule attachment and chromosome alignment, which contribute to genome stability in mitosis. However, the...