Zhen-Rui Chen
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Explore the profile of Zhen-Rui Chen including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
206
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Recent Articles
1.
Zhou Y, Wang J, Zhou I, Lou H, Li C, Chen Z, et al.
PLoS One
. 2013 Nov;
8(11):e80005.
PMID: 24244593
The display of full-length antibody on the cell surface was achieved by fusing a transmembrane domain of the platelet-derived growth factor receptor (PDGFR) to the C-terminus of the heavy chain...
2.
Liu H, Li W, Chen Z, Hu Y, Zhang D, Shen W, et al.
Neurochem Res
. 2013 Jul;
38(10):2072-83.
PMID: 23892989
Inflammatory response plays an important role in the pathogenesis of secondary damage after traumatic brain injury (TBI). The inflammasome is a multiprotein complex involved in innate immunity and a number...
3.
Liu H, Li W, Chen Z, Zhou M, Zhuang Z, Zhang D, et al.
Neurol Sci
. 2012 Oct;
34(7):1173-80.
PMID: 23079850
Despite numerous researches and improvements in the past few years, the precise mechanisms underlying secondary brain injury after trauma remain obscure. Iron is essential for almost all types of cells,...
4.
Ling H, Li W, Zhou M, Tang Y, Chen Z, Hang C
J Surg Res
. 2012 Apr;
179(1):e227-34.
PMID: 22498027
Background: Traumatic brain injury (TBI) can cause gastrointestinal dysfunction and increase intestinal permeability. Nuclear factor kappa B (NF-κB) has been shown to be associated with these intestinal events, but it...
5.
Li C, Liang Z, Chen Z, Lou H, Zhou Y, Zhang Z, et al.
Cell Mol Immunol
. 2011 Dec;
9(2):184-90.
PMID: 22179672
Hepatitis B immunoglobulin (HBIG) is important in the management of hepatitis B virus (HBV) infection. Aiming to develop recombinant monoclonal antibodies as an alternative to HBIG, we report the successful...
6.
Zhou Y, Chen Z, He W, Lou H, Zhang Z, Liu S, et al.
Nan Fang Yi Ke Da Xue Xue Bao
. 2011 Aug;
31(8):1369-73.
PMID: 21868326
Objective: To construct a rheumatoid arthritis-specific full-length fully human mammalian display antibody libraries. Methods: Peripheral blood lymphocytes were isolated from patients with rheumatoid arthritis. The repertoires of kappa light chain...
7.
He W, Li C, Chen Z, Zhou Y, Tan W, Jiang S, et al.
Nan Fang Yi Ke Da Xue Xue Bao
. 2011 Mar;
31(2):308-12.
PMID: 21354918
Objective: To construct a mammalian cell surface display library of full-length human antibodies. Methods: The total RNA was isolated from human peripheral blood mononuclear cells (PBMCs), and the genes encoding...
8.
Zhou I, Zhang Z, Li C, Chen Z, He W, Zhou Y, et al.
Acta Biochim Biophys Sin (Shanghai)
. 2011 Jan;
43(3):232-8.
PMID: 21257624
A unique four-way ligation strategy was developed for rapid construction of a full-length antibody library. A mammalian expression vector was constructed that contained dual mammalian expression cassettes and sequences recognized...
9.
Zhou Y, Chen Z, Li C, He W, Liu S, Jiang S, et al.
Acta Biochim Biophys Sin (Shanghai)
. 2010 Aug;
42(8):575-84.
PMID: 20705599
Development of a versatile mammalian display system is essential for the selection of functional human antibodies with high affinities. Here we described a novel strategy for rapid construction of full-length...
10.
Chen Z, Li C, He W, Zhou Y, Zhang Z, Liu S, et al.
Nan Fang Yi Ke Da Xue Xue Bao
. 2010 May;
30(5):1059-62.
PMID: 20501393
Objective: To construct human renal cell carcinoma patient-specific full-length antibody library using mammalian cell surface display technique. Methods: Peripheral blood mononuclear cells (PBMC) were isolated from patients with renal cell...