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Zhe Cong

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Articles 37
Citations 516
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Recent Articles
1.
Ye Q, Zhang D, Zhang R, Xu Q, Huang X, Huang B, et al.
Nat Commun . 2024 Dec; 15(1):10611. PMID: 39639037
The recent worldwide outbreaks of mpox prioritize the development of a safe and effective mRNA vaccine. The contemporary mpox virus (MPXV) exhibits changing virological and epidemiological features, notably affecting populations...
2.
Cong Z, Wei Y, Chong H, Zhang D, Tong L, Zhang J, et al.
J Control Release . 2024 Oct; 376:530-541. PMID: 39427773
Non-adherence to antiretroviral treatment is a critical obstacle to effectively managing the progression of AIDS and reducing transmission and mortality rates. A promising strategy to address the clinical disadvantages of...
3.
Cong Z, Sun Y, Dang C, Yang C, Zhang J, Lu J, et al.
Biomedicines . 2023 Jun; 11(6). PMID: 37371802
Antiretroviral therapy is capable of inhibiting HIV replication, but it fails to completely achieve a cure due to HIV persistence. The commonly used HIV cure approach is the "shock and...
4.
Liao G, Lau H, Liu Z, Li C, Xu Z, Qi X, et al.
Virol J . 2022 Dec; 19(1):212. PMID: 36494863
The COVID-19 pandemic, caused by the SARS-CoV-2 virus and its variants, has posed unprecedented challenges worldwide. Existing vaccines have limited effectiveness against SARS-CoV-2 variants. Therefore, novel vaccines to match mutated...
5.
Liu X, Zhu X, Wang C, Cao Y, Wang B, Ou H, et al.
Nanomaterials (Basel) . 2022 Jul; 12(13). PMID: 35807971
Optical neural networks (ONN) have become the most promising solution to replacing electronic neural networks, which have the advantages of large bandwidth, low energy consumption, strong parallel processing ability, and...
6.
Sun Y, Zhang J, Tong L, Lu J, Chen T, Wei Q, et al.
STAR Protoc . 2022 Jul; 3(3):101479. PMID: 35776642
Strong cellular immunity contributes to the control of HIV infection. Here, we describe a step-by-step protocol to assess the simian immunodeficiency virus (SIV)-specific CD8 T cell responses by quantifying the...
7.
Lin K, Liu M, Bao L, Lv Q, Zhu H, Li D, et al.
Vaccine . 2022 Jun; 40(32):4609-4616. PMID: 35738970
The mass inoculation of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine to induce herd immunity is one of the most effective measures to fight COVID-19. The vaccination of...
8.
Xu W, Cong Z, Duan Q, Wang Q, Su S, Wang R, et al.
Pharmaceuticals (Basel) . 2022 Apr; 15(4). PMID: 35455421
Recently, a series of highly effective peptide- or protein-based HIV fusion inhibitors have been identified. However, due to their short half-life, their clinical application is limited. Therefore, the development of...
9.
Xue J, Chong H, Zhu Y, Zhang J, Tong L, Lu J, et al.
Cell . 2021 Dec; 185(1):131-144.e18. PMID: 34919814
Two HIV fusion-inhibitory lipopeptides (LP-97 and LP-98) were designed with highly potent, long-acting antiviral activity. Monotherapy using a low dose of LP-98 sharply reduced viral loads and maintained long-term viral...
10.
Tong L, Cong Z, Tian L, Zhang J, Lu J, Lu Q, et al.
Front Microbiol . 2021 Aug; 12:704449. PMID: 34349746
It is challenging to trace the complicated individual-based variations of HIV-specific immunocompetence shift during the successful antiretroviral therapy (ART) era. Using eight rhesus monkeys simulating a longitudinal stage-dependent cohort (baseline-SIV...