Zhanglong Peng
Overview
Explore the profile of Zhanglong Peng including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
602
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0
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Recent Articles
1.
Yang Y, Peng Z, Flores E, Kleinerman E
Cancers (Basel)
. 2022 Sep;
14(17).
PMID: 36077845
Despite aggressive combination chemotherapy and surgery, outcomes for patients with osteosarcoma have remained stagnant for more than 25 years, and numerous clinical trials have identified no new therapies. p53 deletion...
2.
Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase
Bhagat A, Shrestha P, Jeyabal P, Peng Z, Watowich S, Kleinerman E
Front Oncol
. 2022 Aug;
12:947604.
PMID: 36033503
The mechanisms by which Doxorubicin (Dox) causes acute and late cardiotoxicity are not completely understood. One understudied area is the innate immune response, and in particular the role of neutrophils...
3.
Peng Z, Bedi S, Mann V, Sundaresan A, Homma K, Gaskey G, et al.
J Immunol Res
. 2021 May;
2021:8121407.
PMID: 34046506
To mimic Alzheimer's disease, transgenic mice overexpressing the amyloid precursor protein (APP) were used in this study. We hypothesize that the neuroprotective effects of ETAS®50, a standardized extract of stem...
4.
Uray K, Peng Z, Cattano D, Eltzschig H, Doursout M
Am J Transl Res
. 2020 Sep;
12(8):4639-4647.
PMID: 32913537
Background: Chronic heart failure (CHF) is a common and serious complication of patients with ischemic heart disease that may eventually lead to the development of pulmonary fibrosis. While other forms...
5.
Lopez E, Peng Z, Kozar R, Cao Y, Ko T, Wade C, et al.
Shock
. 2019 Aug;
53(2):156-163.
PMID: 31389906
Background: Endothelial dysfunction during hemorrhagic shock (HS) is associated with loss of cell-associated syndecan-1 (Sdc1) and hyperpermeability. Fresh frozen plasma (FFP) preserves Sdc1 and reduces permeability following HS, although the...
6.
Pati S, Peng Z, Wataha K, Miyazawa B, Potter D, Kozar R
PLoS One
. 2018 Feb;
13(2):e0192363.
PMID: 29394283
In severe trauma and hemorrhage the early and empiric use of fresh frozen plasma (FFP) is associated with decreased morbidity and mortality. However, utilization of FFP comes with the significant...
7.
Wu F, Peng Z, Park P, Kozar R
Shock
. 2017 Jan;
48(3):340-345.
PMID: 28107214
Syndecan-1 (Sdc1) is considered a biomarker of injury to the endothelial glycocalyx following hemorrhagic shock, with shedding of Sdc1 deleterious. Resuscitation with fresh frozen plasma (FFP) has been correlated with...
8.
Peng Z, Pati S, Fontaine M, Hall K, Herrera A, Kozar R
J Trauma Acute Care Surg
. 2016 Oct;
81:S171-S176.
PMID: 27768665
Background: Clinical studies have demonstrated that the early and empiric use of plasma improves survival after hemorrhagic shock. We have demonstrated in rodent models of hemorrhagic shock that resuscitation with...
9.
Peng Z, Ban K, LeBlanc A, Kozar R
J Trauma Acute Care Surg
. 2016 Mar;
81(2):358-65.
PMID: 27027557
Background: Intravenous tranexamic acid (TXA) is an effective adjunct after hemorrhagic shock (HS) because of its antifibrinolytic properties. TXA is also a serine protease inhibitor, and recent laboratory data demonstrated...
10.
Deng X, Cao Y, Huby M, Duan C, Baer L, Peng Z, et al.
Shock
. 2015 Aug;
45(1):50-54.
PMID: 26263440
Hemorrhagic shock is the leading cause of preventable deaths in civilian and military trauma. Use of fresh frozen plasma (FFP) in patients requiring massive transfusion is associated with improved outcomes....