Zeneng Cheng
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Explore the profile of Zeneng Cheng including associated specialties, affiliations and a list of published articles.
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87
Citations
771
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Recent Articles
1.
Ye X, Liu F, Cheng Z, Xie F
AAPS J
. 2025 Mar;
27(2):59.
PMID: 40074933
Nevirapine, primarily metabolized by CYP2B6 and CYP3A4, exhibits enzyme auto-induction and significant ethnic variability in its pharmacokinetics (PK). These complexities are further exacerbated in HIV-TB co-infected patients, where nevirapine is...
2.
Liu F, Cheng Z, Li S, Xie F
J Pharmacokinet Pharmacodyn
. 2025 Mar;
52(2):19.
PMID: 40038131
Pharmacokinetics (PK)/pharmacodynamics (PD) modeling and simulation is crucial for optimizing antimicrobial dosing. This study assessed covariate impact on PK variability and identified scenarios where fixing the covariate with median value...
3.
Liu Y, Peng Y, Wu Q, Cheng Z, Xie F, Li S
Anal Sci
. 2025 Mar;
PMID: 40025270
High-performance liquid chromatography coupled with inductively coupled plasma-mass spectrometry (HPLC-ICP-MS) is a promising structure-independent technique for accurate quantification of drug-related substances in pharmaceuticals. In this study, we aimed to develop...
4.
Peng Y, Liu Y, Cheng Z, Zhang Q, Xie F, Zhu S, et al.
Drug Des Devel Ther
. 2025 Feb;
19:1105-1117.
PMID: 39991086
Objective: Extended meropenem infusion is increasingly employed to enhance clinical outcomes in critically ill patients. Nonetheless, investigations into such dosing regimens in renal-impaired patients undergoing continuous renal replacement therapy (CRRT)...
5.
Li S, Ye X, Wang Q, Cheng Z, Liu F, Xie F
CPT Pharmacometrics Syst Pharmacol
. 2024 Oct;
14(1):152-163.
PMID: 39403008
Empirical maturation models (e.g., Johnson and Rhodin models) for glomerular filtration rate (GFR) are commonly used as scaling factors for predicting pediatric renal clearance, but their predictive performance for drugs...
6.
Xu L, Li S, Wu W, Cheng Z, Xie F
AAPS J
. 2024 Jul;
26(4):77.
PMID: 38960976
Dose-scale pharmacodynamic bioequivalence is recommended for evaluating the consistency of generic and innovator formulations of certain locally acting drugs, such as orlistat. This study aimed to investigate the standard methodology...
7.
Xiao W, Zhu Z, Xie F, Liu F, Cheng Z
Pharm Res
. 2024 Mar;
41(5):911-920.
PMID: 38509321
Introduction: PDX-02 (Flurbiprofen sodium) is a topical nonsteroidal anti-inflammatory drug in gel formulation for local analgesia and anti-inflammation. A Phase I clinical trial was conducted to assess the safety, tolerability,...
8.
Shen J, Hu A, Yang Y, Nie T, Huang S, Cheng Z, et al.
Int J Pharm
. 2024 Mar;
654:123989.
PMID: 38467205
The study aimed to address the challenges related to insufficient dissolution and maintenance of supersaturation in binary solid dispersions. Lacidipine, categorized as a BCS class II drug, was employed as...
9.
Nie T, Huang S, Yang Y, Hu A, Wang J, Cheng Z, et al.
Food Funct
. 2024 Feb;
15(6):2836-2859.
PMID: 38414443
Excessive consumption of dietary sodium is a significant contributor to non-communicable diseases, including hypertension and cardiovascular disease. There is now a global consensus that regulating salt intake is among the...
10.
Huang Y, Ji H, Dong J, Wang X, He Z, Cheng Z, et al.
Cancers (Basel)
. 2023 Aug;
15(16).
PMID: 37627085
CircRNAs are crucial in tumorigenesis and metastasis, and are comprehensively downregulated in hepatocellular carcinoma (HCC). Previous studies demonstrated that the back-splicing of circRNAs was closely related to 3'-end splicing. As...