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Zefang Tang

Explore the profile of Zefang Tang including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 8322
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Recent Articles
1.
Tang Z, Luo S, Zeng H, Huang J, Sui X, Wu M, et al.
Nat Methods . 2024 Sep; 21(10):1818-1829. PMID: 39294367
Spatial omics technologies characterize tissue molecular properties with spatial information, but integrating and comparing spatial data across different technologies and modalities is challenging. A comparative analysis tool that can search,...
2.
Sui X, Lo J, Luo S, He Y, Tang Z, Lin Z, et al.
bioRxiv . 2024 Aug; PMID: 39149316
Characterizing the transcriptional and translational gene expression patterns at the single-cell level within their three-dimensional (3D) tissue context is essential for revealing how genes shape tissue structure and function in...
3.
Shi H, He Y, Zhou Y, Huang J, Maher K, Wang B, et al.
Nature . 2023 Dec; 625(7993):E6. PMID: 38066327
No abstract available.
4.
Shi H, He Y, Zhou Y, Huang J, Maher K, Wang B, et al.
Nature . 2023 Sep; 622(7983):552-561. PMID: 37758947
Spatially charting molecular cell types at single-cell resolution across the 3D volume is critical for illustrating the molecular basis of brain anatomy and functions. Single-cell RNA sequencing has profiled molecular...
5.
Zeng H, Huang J, Ren J, Wang C, Tang Z, Zhou H, et al.
Science . 2023 Jun; 380(6652):eadd3067. PMID: 37384709
The precise control of messenger RNA (mRNA) translation is a crucial step in posttranscriptional gene regulation of cellular physiology. However, it remains a challenge to systematically study mRNA translation at...
6.
Zeng H, Huang J, Zhou H, Meilandt W, Dejanovic B, Zhou Y, et al.
Nat Neurosci . 2023 Feb; 26(3):430-446. PMID: 36732642
Complex diseases are characterized by spatiotemporal cellular and molecular changes that may be difficult to comprehensively capture. However, understanding the spatiotemporal dynamics underlying pathology can shed light on disease mechanisms...
7.
Li C, Tang Z, Zhang W, Ye Z, Liu F
Nucleic Acids Res . 2021 May; 49(W1):W242-W246. PMID: 34050758
In 2017, we released GEPIA (Gene Expression Profiling Interactive Analysis) webserver to facilitate the widely used analyses based on the bulk gene expression datasets in the TCGA and the GTEx...
8.
Tang Z, Yu Y, Ng K, Sow D, Hu J, Mei J
J Biomed Inform . 2021 Jan; 115:103686. PMID: 33493631
Objective: As Electronic Health Records (EHR) data accumulated explosively in recent years, the tremendous amount of patient clinical data provided opportunities to discover real world evidence. In this study, a...
9.
Zhu D, Xu R, Huang X, Tang Z, Tian Y, Zhang J, et al.
Cell Death Differ . 2020 Dec; 28(6):1773-1789. PMID: 33328570
Upregulation of programmed death ligand 1 (PD-L1) helps tumor cells escape from immune surveillance, and therapeutic antibodies targeting PD-1/PD-L1 have shown better patient outcomes only in several types of malignancies....
10.
Tang Z, Chen T, Ren X, Zhang Z
J Genet Genomics . 2019 Oct; 46(9):413-421. PMID: 31630971
The Cancer Genome Atlas (TCGA) project produced RNA-Seq data for tens of thousands of cancer and non-cancer samples with clinical survival information, providing an unprecedented opportunity for analyzing prognostic genes...