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Zaydah R de Laurent

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Articles 27
Citations 335
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Recent Articles
1.
Kamel W, Ruscica V, Embarc-Buh A, de Laurent Z, Garcia-Moreno M, Demyanenko Y, et al.
Mol Cell . 2024 Dec; 84(24):4896-4911.e7. PMID: 39642884
RNA is a central molecule for viruses; however, the interactions that viral RNA (vRNA) establishes with the host cell is only starting to be elucidated. Here, we determine the ribonucleoprotein...
2.
Owuor D, de Laurent Z, Oketch J, Murunga N, Otieno J, Nabakooza G, et al.
Sci Rep . 2024 Aug; 14(1):18987. PMID: 39152215
The role of sub-Saharan Africa in the global spread of influenza viruses remains unclear due to insufficient spatiotemporal sequence data. Here, we analyzed 222 codon-complete sequences of influenza A viruses...
3.
Owuor D, de Laurent Z, Nyawanda B, Emukule G, Kondor R, Barnes J, et al.
Sci Rep . 2023 Dec; 13(1):22342. PMID: 38102198
Influenza viruses undergo rapid evolutionary changes, which requires continuous surveillance to monitor for genetic and potential antigenic changes in circulating viruses that can guide control and prevention decision making. We...
4.
Makori T, Bargul J, Lambisia A, Mwanga M, Murunga N, de Laurent Z, et al.
Virus Evol . 2023 May; 9(1):vead025. PMID: 37207000
The introduction of rotavirus vaccines into the national immunization programme in many countries has led to a decline in childhood diarrhoea disease burden. Coincidentally, the incidence of some rotavirus group...
5.
Nabakooza G, Owuor D, de Laurent Z, Galiwango R, Owor N, Kayiwa J, et al.
Sci Rep . 2023 Apr; 13(1):5516. PMID: 37015946
Genetic characterisation of circulating influenza viruses directs annual vaccine strain selection and mitigation of infection spread. We used next-generation sequencing to locally generate whole genomes from 116 A(H1N1)pdm09 and 118...
6.
Tegally H, San J, Cotten M, Moir M, Tegomoh B, Mboowa G, et al.
Science . 2022 Sep; 378(6615):eabq5358. PMID: 36108049
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been...
7.
Morobe J, Pool B, Marie L, Didon D, Lambisia A, Makori T, et al.
Viruses . 2022 Jun; 14(6). PMID: 35746789
Seychelles, an archipelago of 155 islands in the Indian Ocean, had confirmed 24,788 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the 31st of December 2021. The first...
8.
Kimenyi K, Wamae K, Ngoi J, de Laurent Z, Ndwiga L, Osoti V, et al.
Malar J . 2022 Jun; 21(1):192. PMID: 35725456
Background: High levels of genetic diversity are common characteristics of Plasmodium falciparum parasite populations in high malaria transmission regions. There has been a decline in malaria transmission intensity over 12...
9.
Agoti C, Ochola-Oyier L, Dellicour S, Mohammed K, Lambisia A, de Laurent Z, et al.
Elife . 2022 Jun; 11. PMID: 35699426
Background: Detailed understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) regional transmission networks within sub-Saharan Africa is key for guiding local public health interventions against the pandemic. Methods: Here,...
10.
Nyamwaya D, Otiende M, Mwango L, Kariuki S, Otieno B, Omuoyo D, et al.
PLoS Med . 2022 May; 19(5):e1003994. PMID: 35550620
Background: Neurological complications due to chikungunya virus (CHIKV) infection have been described in different parts of the world, with children being disproportionately affected. However, the burden of CHIKV-associated neurological disease...