Zakaria Louadi
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Explore the profile of Zakaria Louadi including associated specialties, affiliations and a list of published articles.
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9
Citations
127
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Recent Articles
1.
Kersting J, Lazareva O, Louadi Z, Baumbach J, Blumenthal D, List M
Br J Pharmacol
. 2024 Dec;
PMID: 39631757
Background And Purpose: Gene regulation is frequently altered in diseases in unique and patient-specific ways. Hence, personalised strategies have been proposed to infer patient-specific gene-regulatory networks. However, existing methods do...
2.
Hackl L, Fenn A, Louadi Z, Baumbach J, Kacprowski T, List M, et al.
NAR Genom Bioinform
. 2023 Sep;
5(3):lqad081.
PMID: 37705830
MicroRNAs (miRNAs) are small non-coding RNA molecules that bind to target sites in different gene regions and regulate post-transcriptional gene expression. Approximately 95% of human multi-exon genes can be spliced...
3.
Fenn A, Tsoy O, Faro T, Rossler F, Dietrich A, Kersting J, et al.
NAR Genom Bioinform
. 2023 Jun;
5(2):lqad044.
PMID: 37260511
Alternative splicing is a major contributor to transcriptome and proteome diversity in health and disease. A plethora of tools have been developed for studying alternative splicing in RNA-seq data. Previous...
4.
Lio C, Grabert G, Louadi Z, Fenn A, Baumbach J, Kacprowski T, et al.
Bioinformatics
. 2022 Dec;
39(1).
PMID: 36579860
Motivation: During disease progression or organism development, alternative splicing may lead to isoform switches that demonstrate similar temporal patterns and reflect the alternative splicing co-regulation of such genes. Tools for...
5.
Louadi Z, Elkjaer M, Klug M, Lio C, Fenn A, Illes Z, et al.
Genome Biol
. 2021 Dec;
22(1):327.
PMID: 34857024
Alternative splicing (AS) is an important aspect of gene regulation. Nevertheless, its role in molecular processes and pathobiology is far from understood. A roadblock is that tools for the functional...
6.
Matschinske J, Alcaraz N, Benis A, Golebiewski M, Grimm D, Heumos L, et al.
Nat Methods
. 2021 Aug;
18(10):1128-1131.
PMID: 34433960
No abstract available.
7.
Louadi Z, Yuan K, Gress A, Tsoy O, Kalinina O, Baumbach J, et al.
Nucleic Acids Res
. 2020 Sep;
49(D1):D309-D318.
PMID: 32976589
Alternative splicing plays a major role in regulating the functional repertoire of the proteome. However, isoform-specific effects to protein-protein interactions (PPIs) are usually overlooked, making it impossible to judge the...
8.
Louadi Z, Oubounyt M, Tayara H, Chong K
Genes (Basel)
. 2019 Aug;
10(8).
PMID: 31374967
Alternative splicing (AS) is the process of combining different parts of the pre-mRNA to produce diverse transcripts and eventually different protein products from a single gene. In computational biology field,...
9.
Oubounyt M, Louadi Z, Tayara H, Chong K
Front Genet
. 2019 Apr;
10:286.
PMID: 31024615
The promoter region is located near the transcription start sites and regulates transcription initiation of the gene by controlling the binding of RNA polymerase. Thus, promoter region recognition is an...