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» Authors » Zaira Tomasoni

Zaira Tomasoni

Explore the profile of Zaira Tomasoni including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 10
Followers 0
Related Specialties
Pharmacology
Molecular Biology
Biochemistry
Top 10 Co-Authors
Chiara Fiorentini
Federica Bono
Veronica Mutti
Cristina Missale
Giulia Sbrini
Federica Giona
Raffaele Badolato
Silvia Bolognin
Carrie K Jones
Stefania Beretta
Published In
Mol Neurobiol
Biomolecules
Mol Psychiatry
Curr Top Behav Neurosci
Stem Cell Res
Affiliations
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Recent Articles
1.
Shank3 modulates Rpl3 expression and protein synthesis via mGlu5: implications for Phelan McDermid syndrome
Giona F, Beretta S, Zippo A, Stefanoni A, Tomasoni Z, Vicidomini C, et al.
Mol Psychiatry . 2025 Mar; PMID: 40089604
Mutations or deletions in the SHANK3 gene have been identified in up to 1% of autism spectrum disorder cases and are considered the primary cause of neuropsychiatric symptoms in Phelan...
2.
17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine D3/acetylcholine nicotinic receptor heteromer in dopaminergic neurons
Sbrini G, Mutti V, Bono F, Tomasoni Z, Fadel D, Missale C, et al.
Eur J Pharmacol . 2024 May; 976:176678. PMID: 38821163
Dopaminergic neurons express a heteromer composed of the dopamine D3 receptor and the α4β2 nicotinic acetylcholine receptor, the D3R-nAChR heteromer, activated by both nicotine and dopamine D2 and D3 receptors...
3.
Generation of human induced pluripotent stem cell lines derived from three Noonan syndrome patients from a single family carrying the heterozygous PTPN11 c.188 A > G (p.Y63C) mutation
Sbrini G, Tomasoni Z, Cutri M, Pilotta A, Mingotti C, Badolato R, et al.
Stem Cell Res . 2023 Dec; 74:103293. PMID: 38160629
We have established Noonan syndrome (NS)-derived induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of a family cohort carrying the heterozygous PTPN11 c.188 A > ...
4.
G Protein-Dependent Activation of the PKA-Erk1/2 Pathway by the Striatal Dopamine D1/D3 Receptor Heteromer Involves Beta-Arrestin and the Tyrosine Phosphatase Shp-2
Bono F, Tomasoni Z, Mutti V, Sbrini G, Kumar R, Longhena F, et al.
Biomolecules . 2023 Mar; 13(3). PMID: 36979407
The heteromer composed of dopamine D1 and D3 receptors (D1R-D3R) has been defined as a structure able to trigger Erk1/2 and Akt signaling in a G protein-independent, beta-arrestin 1-dependent way...
5.
Central nervous system interaction and crosstalk between nAChRs and other ionotropic and metabotropic neurotransmitter receptors
Bono F, Fiorentini C, Mutti V, Tomasoni Z, Sbrini G, Trebesova H, et al.
Pharmacol Res . 2023 Feb; 190:106711. PMID: 36854367
Neuronal nicotinic acetylcholine receptors (nAChRs) are widely distributed in both the peripheral and the central nervous systems. nAChRs exert a crucial modulatory influence on several brain biological processes; they are...
6.
Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function
Bono F, Mutti V, Tomasoni Z, Sbrini G, Missale C, Fiorentini C
Curr Top Behav Neurosci . 2022 May; 60:47-72. PMID: 35505059
G protein-coupled receptors (GPCR) heterodimers represent new entities with unique pharmacological, signalling, and trafficking properties, with specific distribution restricted to those cells where the two interacting receptors are co-expressed. Like...
7.
Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway
Mutti V, Bono F, Tomasoni Z, Bontempi L, Guglielmi A, Bolognin S, et al.
Mol Neurobiol . 2022 Jan; 59(4):2129-2149. PMID: 35044626
We have previously shown that the heteromer composed by the dopamine D3 receptor (D3R) and the nicotinic acetylcholine receptor (nAChR) (D3R-nAChR heteromer) is expressed in dopaminergic neurons, activated by nicotine...