Zachary S Fredericksen
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Explore the profile of Zachary S Fredericksen including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Holtan S, OConnor H, Fredericksen Z, Liebow M, Thompson C, Macon W, et al.
Int J Cancer
. 2011 Nov;
131(5):1158-68.
PMID: 22038870
Antioxidants, primarily from fruits and vegetables, have been hypothesized to protect against non-Hodgkin lymphoma (NHL). The oxygen radical absorbance capacity (ORAC) assay, which measures total antioxidant capacity of individual foods...
12.
Cerhan J, Fredericksen Z, Wang A, Habermann T, Kay N, Macon W, et al.
Int J Mol Epidemiol Genet
. 2011 Jun;
2(2):95-113.
PMID: 21686124
We present the design features and implementation of a clinic-based case-control study on the molecular epidemiology of lymphoma conducted at the Mayo Clinic (Rochester, Minnesota, USA), and then assess the...
13.
Broeks A, Schmidt M, Sherman M, Couch F, Hopper J, Dite G, et al.
Hum Mol Genet
. 2011 May;
20(16):3289-303.
PMID: 21596841
Breast cancers demonstrate substantial biological, clinical and etiological heterogeneity. We investigated breast cancer risk associations of eight susceptibility loci identified in GWAS and two putative susceptibility loci in candidate genes...
14.
Smedby K, Foo J, Skibola C, Darabi H, Conde L, Hjalgrim H, et al.
PLoS Genet
. 2011 May;
7(4):e1001378.
PMID: 21533074
Non-Hodgkin lymphoma (NHL) represents a diverse group of hematological malignancies, of which follicular lymphoma (FL) is a prevalent subtype. A previous genome-wide association study has established a marker, rs10484561 in...
15.
Walker L, Fredericksen Z, Wang X, Tarrell R, Pankratz V, Lindor N, et al.
Breast Cancer Res
. 2010 Dec;
12(6):R102.
PMID: 21114847
Introduction: Current attempts to identify genetic modifiers of BRCA1 and BRCA2 associated risk have focused on a candidate gene approach, based on knowledge of gene functions, or the development of...
16.
Gaudet M, Kirchhoff T, Green T, Vijai J, Korn J, Guiducci C, et al.
PLoS Genet
. 2010 Nov;
6(10):e1001183.
PMID: 21060860
The considerable uncertainty regarding cancer risks associated with inherited mutations of BRCA2 is due to unknown factors. To investigate whether common genetic variants modify penetrance for BRCA2 mutation carriers, we...
17.
Kelly J, Novak A, Fredericksen Z, Liebow M, Ansell S, Dogan A, et al.
Cancer Epidemiol Biomarkers Prev
. 2010 Sep;
19(11):2847-58.
PMID: 20855536
Background: The t(14;18)(q32;q21) translocation is the most commonly observed chromosomal translocation in non-Hodgkin's lymphoma (NHL), resulting in constitutive Bcl-2 expression and apoptosis inhibition. In addition, germline variation in both BCL2L11...
18.
Antoniou A, Wang X, Fredericksen Z, McGuffog L, Tarrell R, Sinilnikova O, et al.
Nat Genet
. 2010 Sep;
42(10):885-92.
PMID: 20852631
Germline BRCA1 mutations predispose to breast cancer. To identify genetic modifiers of this risk, we performed a genome-wide association study in 1,193 individuals with BRCA1 mutations who were diagnosed with...
19.
Stacey S, Sulem P, Zanon C, Gudjonsson S, Thorleifsson G, Helgason A, et al.
PLoS Genet
. 2010 Jul;
6(7):e1001029.
PMID: 20661439
We used an approach that we term ancestry-shift refinement mapping to investigate an association, originally discovered in a GWAS of a Chinese population, between rs2046210[T] and breast cancer susceptibility. The...
20.
Kelemen L, Goodman M, McGuire V, Rossing M, Webb P, Kobel M, et al.
Cancer Epidemiol Biomarkers Prev
. 2010 Jun;
19(7):1822-30.
PMID: 20570913
Background: We previously reported the risks of ovarian carcinoma for common polymorphisms in one-carbon transfer genes. We sought to replicate associations for DPYD rs1801265, DNMT3A rs13420827, MTHFD1 rs1950902, MTHFS rs17284990,...