Zachary L Nimchuk
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Explore the profile of Zachary L Nimchuk including associated specialties, affiliations and a list of published articles.
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1213
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Recent Articles
21.
Whitewoods C, Cammarata J, Nemec Venza Z, Sang S, Crook A, Aoyama T, et al.
Curr Biol
. 2018 Jul;
28(15):2365-2376.e5.
PMID: 30033333
How genes shape diverse plant and animal body forms is a key question in biology. Unlike animal cells, plant cells are confined by rigid cell walls, and cell division plane...
22.
Soyars C, Peterson B, Burr C, Nimchuk Z
Plant Cell Physiol
. 2018 Jun;
59(8):1608-1620.
PMID: 29912402
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated nuclease 9 (Cas9) system is a genome editing technology transforming the field of plant biology by virtue of the system's efficiency and...
23.
Moody L, Kelly S, Coudert Y, Nimchuk Z, Harrison C, Langdale J
New Phytol
. 2018 Mar;
218(3):1270-1277.
PMID: 29498048
Forward genetics is now straightforward in the moss Physcomitrella patens, and large mutant populations can be screened relatively easily. However, perturbation of development before the formation of gametes currently leaves...
24.
Hodgens C, Nimchuk Z, Kieber J
PLoS One
. 2017 Nov;
12(11):e0188406.
PMID: 29141013
Genetic manipulation of organisms using CRISPR/Cas9 technology generally produces small insertions/deletions (indels) that can be difficult to detect. Here, we describe a technique to easily and rapidly identify such indels....
25.
Denbow C, Lapins S, Dietz N, Scherer R, Nimchuk Z, Okumoto S
Front Plant Sci
. 2017 Jul;
8:1171.
PMID: 28725235
CRISPR-Cas9 system rapidly became an indispensable tool in plant biology to perform targeted mutagenesis. A CRISPR-Cas9-mediated double strand break followed by non-homologous end joining (NHEJ) repair most frequently results in...
26.
Moussu S, Doll N, Chamot S, Brocard L, Creff A, Fourquin C, et al.
Plant Cell
. 2017 Jul;
29(7):1642-1656.
PMID: 28696222
seed development requires the concomitant development of two zygotic compartments, the embryo and the endosperm. Following fertilization, the endosperm expands and the embryo grows invasively through the endosperm, which breaks...
27.
Nimchuk Z, Perdue T
Front Plant Sci
. 2017 Jun;
8:773.
PMID: 28579995
Live imaging of above ground meristems can lead to new insights in plant development not possible from static imaging of fixed tissue. The use of an upright confocal microscope offers...
28.
Nimchuk Z
PLoS Genet
. 2017 Mar;
13(3):e1006681.
PMID: 28355208
The regulation of stem cell proliferation in plants is controlled by intercellular signaling pathways driven by the diffusible CLAVATA3 (CLV3p) peptide. CLV3p perception is thought to be mediated by an...
29.
Nishimura M, Anderson R, Cherkis K, Law T, Liu Q, Machius M, et al.
Proc Natl Acad Sci U S A
. 2017 Feb;
114(10):E2053-E2062.
PMID: 28137883
Detection of pathogens by plants is mediated by intracellular nucleotide-binding site leucine-rich repeat (NLR) receptor proteins. NLR proteins are defined by their stereotypical multidomain structure: an N-terminal Toll-interleukin receptor (TIR)...
30.
Liu Y, Miao J, Traore S, Kong D, Liu Y, Zhang X, et al.
Front Mol Biosci
. 2016 Nov;
3:70.
PMID: 27833912
overgrowth is a common problem in -mediated plant transformation. To suppress the overgrowth, various antibiotics have been used during plant tissue culture steps. The antibiotics are expensive and may adversely...