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Zachary A Szpiech

Explore the profile of Zachary A Szpiech including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 3292
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Recent Articles
1.
Massey D, Szpiech Z, Goldberg A
Genetics . 2025 Feb; PMID: 39919029
Population genetic theory, and the empirical methods built upon it, often assume that individuals pair randomly for reproduction. However, natural populations frequently violate this assumption, which may potentially confound genome-wide...
2.
Assis B, Sullivan A, Marciniak S, Bergey C, Garcia V, Szpiech Z, et al.
Nat Commun . 2025 Jan; 16(1):89. PMID: 39746982
Understanding the process of genetic adaptation in response to human-mediated ecological change will help elucidate the eco-evolutionary impacts of human activity. In the 1930s red imported fire ants (Solenopsis invicta)...
3.
Calderon A, Wood A, Szpiech Z, Toews D
Evol Appl . 2024 Dec; 17(12):e70052. PMID: 39655065
The Kirtland's warbler () is a rare migratory passerine species and habitat specialist of the North American Jack Pine Forests. Their near extinction in the 1970s classified them as endangered...
4.
Ciccarella M, Laurent R, Szpiech Z, Patin E, Dessarps-Freichey F, Utge J, et al.
bioRxiv . 2024 Nov; PMID: 39484499
Human admixture history is rarely a simple process in which distinct populations, previously isolated for a long time, come into contact once to form an admixed population. In this study,...
5.
Yoo D, Rhie A, Hebbar P, Antonacci F, Logsdon G, Solar S, et al.
bioRxiv . 2024 Aug; PMID: 39131277
We present haplotype-resolved reference genomes and comparative analyses of six ape species, namely: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan, and siamang. We achieve chromosome-level contiguity with unparalleled sequence accuracy...
6.
Leon-Apodaca A, Kumar M, Del Castillo A, Conroy G, Lamont R, Ogbourne S, et al.
Genome Biol Evol . 2024 Jun; 16(7). PMID: 38913571
Dingoes come from an ancient canid lineage that originated in East Asia around 8,000 to 11,000 years BP. As Australia's largest terrestrial predator, dingoes play an important ecological role. A...
7.
Massey D, Szpiech Z, Goldberg A
bioRxiv . 2024 Jun; PMID: 38895317
Population genetic theory, and the empirical methods built upon it, often assume that individuals pair randomly for reproduction. However, natural populations frequently violate this assumption, which may potentially confound genome-wide...
8.
Makova K, Pickett B, Harris R, Hartley G, Cechova M, Pal K, et al.
Nature . 2024 May; 630(8016):401-411. PMID: 38811727
Apes possess two sex chromosomes-the male-specific Y chromosome and the X chromosome, which is present in both males and females. The Y chromosome is crucial for male reproduction, with deletions...
9.
Steux C, Szpiech Z
Genome Biol Evol . 2024 May; 16(6). PMID: 38795368
Understanding how deleterious variation is shaped and maintained in natural populations is important in conservation and evolutionary biology, as decreased fitness caused by these deleterious mutations can potentially lead to...
10.
Sweetalana , Nataneli S, Huang S, Mooney J, Szpiech Z
bioRxiv . 2024 May; PMID: 38746159
Runs of homozygosity (ROH) are genomic regions that arise when two copies of identical haplotypes are inherited from a shared common ancestor. In this study, we leverage ROH to identify...