Zach Sergi
Overview
Explore the profile of Zach Sergi including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
5
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Recent Articles
1.
Kim O, Sergi Z, Yu G, Yamamoto K, Quezado M, Abdullaev Z, et al.
Acta Neuropathol Commun
. 2024 Sep;
12(1):148.
PMID: 39256867
Malignant transformation (MT) is commonly seen in IDH-mutant gliomas. There has been a growing research interest in revealing its underlying mechanisms and intervening prior to MT at the early stages...
2.
Pang Y, Li Q, Sergi Z, Yu G, Sang X, Kim O, et al.
bioRxiv
. 2023 Oct;
PMID: 37786680
Highlights: Zotiraciclib (ZTR), a CDK9 inhibitor, hinders IDH-mutant glioma growth and . ZTR halts cell cycle, disrupts respiration, and induces oxidative stress in IDH-mutant cells.ZTR unexpectedly inhibits PIM kinases, impacting...
3.
Kim O, Butler M, Sergi Z, Robey R, Zhang M, Chari R, et al.
Neurooncol Adv
. 2023 Sep;
5(1):vdad102.
PMID: 37706203
Background: Deletions or loss-of-function mutations in phosphatase and tensin homolog () are common in glioblastoma (GBM) and have been associated with defective DNA damage repair. Here we investigated whether PTEN...
4.
Merchant M, Raygada M, Pang Y, Quezado M, Raffeld M, Xi L, et al.
Front Oncol
. 2022 Aug;
12:954879.
PMID: 35982947
Most tumors, including brain tumors, are sporadic. However, a small subset of CNS tumors are associated with hereditary cancer conditions like Lynch Syndrome (LS). Here, we present a case of...