Zach Madaj
Overview
Explore the profile of Zach Madaj including associated specialties, affiliations and a list of published articles.
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6
Citations
65
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0
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Recent Articles
1.
Lubben N, Brynildsen J, Webb C, Li H, Leyns C, Changolkar L, et al.
Transl Neurodegener
. 2024 Mar;
13(1):13.
PMID: 38438877
Background: Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson's disease (PD). These mutations elevate the LRRK2 kinase activity, making LRRK2 kinase inhibitors an...
2.
Sha Q, Fu Z, Escobar Galvis M, Madaj Z, Underwood M, Steiner J, et al.
Mol Psychiatry
. 2023 Nov;
29(1):134-145.
PMID: 37938766
Suicide rates have increased steadily world-wide over the past two decades, constituting a serious public health crisis that creates a significant burden to affected families and the society as a...
3.
Sha Q, Madaj Z, Keaton S, Escobar Galvis M, Smart L, Krzyzanowski S, et al.
Transl Psychiatry
. 2022 Jan;
12(1):35.
PMID: 35078975
Depression during and after pregnancy affects up to 20% of pregnant women, but the biological underpinnings remain incompletely understood. As pregnancy progresses, the immune system changes to facilitate fetal development,...
4.
Schipper J, Westerhuis J, Beddows I, Madaj Z, Monsma D, Hostetter G, et al.
Int J Cancer
. 2020 May;
147(8):2265-2278.
PMID: 32388866
The microenvironment of pancreatic cancer adenocarcinoma (PDAC) is highly desmoplastic with distinct tumor-restraining and tumor-promoting fibroblast subpopulations. Re-education rather than indiscriminate elimination of these fibroblasts has emerged as a new...
5.
Kenyon E, Westerhuis J, Volk M, Hix J, Chakravarty S, Claucherty E, et al.
Breast Cancer Res
. 2019 Nov;
21(1):129.
PMID: 31779648
Background: Prophylactic mastectomy is the most effective intervention to prevent breast cancer. However, this major surgery has life-changing consequences at the physical, emotional, psychological, and social levels. Therefore, only high-risk...
6.
Ganguly S, Daft P, Cao J, Meng X, Zhong Z, Vander Ark A, et al.
Cancers (Basel)
. 2018 Nov;
10(12).
PMID: 30469488
The role of myeloid cell-specific TGF-β signaling in non-small-cell lung cancer (NSCLC)-induced osteolytic bone lesion development is unknown. We used a genetically engineered mouse model, knockout (KO), which has a...