Z Kristofikova
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Explore the profile of Z Kristofikova including associated specialties, affiliations and a list of published articles.
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26
Citations
43
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Recent Articles
1.
Soukup O, Kristofikova Z, Jun D, Tambor V, ripova D, Kuca K
Toxicol Lett
. 2012 Jun;
212(3):315-9.
PMID: 22683831
Organophosphorus poisoning manifests as a cholinergic syndrome due to an inhibition of acetylcholinesterase. It is treated symptomatically by anticholinergics and oxime reactivators are used as causal antidotes. Reactivators possess a...
2.
Soukup O, Kristofikova Z, Proska J, Tobin G, Patocka J, Marek J, et al.
Biomed Pharmacother
. 2010 Jul;
64(8):541-5.
PMID: 20634031
The oxime reactivator K112 is a member of the new group of xylene linker-containing AChE reactivators. Its cholinergic properties could be of importance at OP poisoning and are not related...
3.
Kristofikova Z, Ricny J, Kozmikova I, ripova D, Zach P, Klaschka J
Neurochem Res
. 2006 May;
31(3):351-60.
PMID: 16733811
It is suggested that amyloid beta peptides (Abeta) play a role in the pathogenesis of Alzheimer disease but their physiological function is still unknown. However, low pM-nM concentrations mediate a...
4.
Kristofikova Z, Cermak M, Benesova O, Klaschka J, Zach P
Neurochem Res
. 2005 May;
30(2):253-62.
PMID: 15895829
Our previous experiments indicated an age- and sex-dependent functional lateralization of a high-affinity choline uptake system in hippocampi of Wistar rats. The system is connected with acetylcholine synthesis and also...
5.
Benesova O, Tejkalova H, Kristofikova Z, Husek P, Nedvidkova J, Yamamotova A
Eur Neuropsychopharmacol
. 2001 Oct;
11(5):367-73.
PMID: 11597823
The risk of neurodevelopmental toxicity was studied in indomethacin (INDO), an inhibitor of prostaglandin synthesis, which is used in at-risk neonates to prevent the consequences of brain intraventricular haemorrhage or...
6.
Kristofikova Z, Tejkalova H, Klaschka J
Neurochem Res
. 2001 Aug;
26(3):203-12.
PMID: 11495543
Effects of amyloid beta peptide 1-40 (Abeta) and of plant cysteine proteases bromelain and papain on the high-affinity uptake of choline (HACU) and the specific binding of [3H]hemicholinium-3 ([3H]HC-3) have...
7.
Benesova O, Tejkalova H, Kristofikova Z, Panajotova V, Husek P
Gen Physiol Biophys
. 2000 Mar;
18 Spec No:21-7.
PMID: 10703715
The risk of functional teratogenicity of two drugs used in neonatal pharmacotherapy was studied: indomethacin (INDO) and dexamethasone (DEX). Model experiments were carried out in Wistar strain rats, breed Konárovice,...
8.
Kristofikova Z, Klaschka J, Tejkalova H
Neurochem Res
. 1998 Aug;
23(7):923-9.
PMID: 9690733
The Na+-dependent high-affinity choline uptake (HACU) transport and the [3H]hemicholinium-3 ([3H]HC-3) specific binding were measured on hippocampal synaptosomes of young (3-6 months) and old (22 months) Wistar rats. In vitro...
9.
Kristofikova Z, Majer E, Fales E, Pekny I, Klaschka J
Dement Geriatr Cogn Disord
. 1998 Feb;
9(1):6-12.
PMID: 9469258
Basal and stimulated (by L-glutamic acid, GA) levels of thiobarbituric-acid-reactive products were estimated in the brain tissue (hippocampus, cortex and cerebellum) from autopsy samples of people with Alzheimer disease (AD),...
10.
Kristofikova Z, Klaschka J
Neurochem Res
. 1997 Jan;
22(1):67-73.
PMID: 9021765
A second messenger role for arachidonic acid (AA) in the regulation of the high-affinity choline uptake (HACU) was suggested. It was reported that micromolar concentrations of AA applied in vitro...